Sökning: "protein translocation machinery"

Visar resultat 11 - 15 av 25 avhandlingar innehållade orden protein translocation machinery.

  1. 11. Elongation factor 2: A key component of the translation machinery in eukaryotes : Properties of yeast elongation factor 2 studied in vivo

    Författare :Galyna Bartish; Odd Nygård; Suparna Sanyal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Elongation factor 2; yeast; ribosome; phosphorylation; Switch I; site-directed mutagenesis; functional complementation; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : Synthesis of proteins is performed by the ribosome, a large ribonucleoprotein complex. Apart from the ribosome, numerous protein factors participate in this process. Elongation factor 2 (eEF2) is one of these factors. eEF2 is an essential protein with a mol. LÄS MER

  3. 12. Characterization of cholorplast protein import in Arabidopsis thaliana with emphasis on Toc64 and Tic55

    Författare :Patrik Boij; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chloroplast import; non-essential receptor; Toc64; redox control; Tic55; DEPC; substrate dependent pathway; PTC52; proteomics;

    Sammanfattning : Although the chloroplast possesses a genome of its own most genes have been transferred during the evolution to the nucleus to acquire more transcriptional control, and couple the activities of the wh... merole cell to events at the chloroplast. LÄS MER

  4. 13. The biological role and clinical impact of SYT-SSX fusion gene and IGF-1R in synovial sarcoma

    Författare :Yuntao Xie; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Synovial sarcoma; translocation; SYT-SSX; IGF-1R cyclin D1; cell cycle; proliferation; apoptosis.;

    Sammanfattning : Synovial sarcoma, which is a highly malignant soft tissue tumour occurring mainly in young and middle-aged adults, is characterized by the translocation t(X; 18)(p 11.2; q 11.2). LÄS MER

  5. 14. Epac2 signaling at the β-cell plasma membrane

    Författare :Ida Alenkvist; Anders Tengholm; Olga Göransson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-cell; insulin secretion; cAMP; Ca2 ; Epac; Rap; exocytosis; sulfonylurea; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Secretion of appropriate amounts of insulin from pancreatic β-cells is crucial for glucose homeostasis. The β-cells release insulin in response to glucose and other nutrients, hormones and neurotransmitters, which trigger intracellular signaling cascades, that result in exocytotic fusion of insulin-containing vesicles with the plasma membrane. LÄS MER

  7. 15. Nuclear compartmentalization of viral and cellular proteins involved in gamma-herpes virus (EBV and HHV-8) mediated cellular transformation

    Författare :Karin Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :EBV; HHV-8; latency; PML nuclear body; fluorescence microscopy;

    Sammanfattning : The aim of the work described in this thesis has been to characterize the nuclear compartmentalization of cellular and viral proteins involved in EBV or HHV-8 mediated cellular transformation. We have studied the EBV encoded EBNA-5 and its association with the PML nuclear bodies (NBs) and nuclear inclusions. LÄS MER