Sökning: "prognostic marker"

Visar resultat 16 - 20 av 245 avhandlingar innehållade orden prognostic marker.

1. 16. Refined diagnosis and prognosis in soft tissue sarcoma - genetic profiles, biomarkers and prognostic models

   Författare :Ana Carneiro; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MFH; microarrays; prognostic factors; metastasis; local recurrence; proliferation; Ki67; Top2a; p21; p27; S-phase fraction; erzin.;

   Sammanfattning : This work aimed at evaluate diagnosis and prognosis in soft tissue sarcoma (STS): In study I, 32K bacterial artificial chromosome (BAC) arrays and gene expression profiling were applied to 18 leiomyosarcomas and 31 undifferentiated pleomorphic sarcomas (UPS), with the aim of identifying molecular subtype signatures. Both the gains/losses profiles and the gene expression signatures revealed striking similarities between the two tumour types. LÄS MER

3. 17. Prognostic factors in renal cell carcinoma : evaluation of erythropoietin and its receptor, carbonic anhydrase IX, parathyroid hormone-related protein and osteopontin

   Författare :Karin Papworth; Torgny Rasmuson; Börje Ljungberg; Kjell Grankvist; Sten Nilsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Renal cell carcinoma; EPO; EPO-R; CA IX; PTHrP; OPN; prognosis; Oncology; Onkologi; onkologi; Oncology;

   Sammanfattning : A prognostic factor is a marker or a feature that can be used to estimate the risk of recurrence of disease, metastatic spread and clinical outcome. Despite intensive search for more sophisticated markers in renal cell carcinoma (RCC), few have added prognostic information to earlier described factors like stage of disease, nuclear grade, tumour type, and in metastatic disease; performance status, anaemia, hypercalcaemia and increased erythrocyte sedimentation. LÄS MER

4. 18. Clinical studies of RNA as a prognostic and diagnostic marker for disease

   Författare :Helena Isaksson; Torbjörn Nilsson; Bengt Sorbe; Gisela Helenius; Ola Hammarsten; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene expression; ovarian cancer; hypercalprotectinaemia; hyperzincaemia; ischemia; biomarker;

   Sammanfattning : Technologies for RNA detection are evolving rapidly and gives an op-portunity for discovery of new markers for early detection of complex diseases. Today in clinical work we rely on signs and symptoms in com-bination with the measurement of protein levels for diagnosis. LÄS MER

5. 19. DNA methylation as a prognostic marker in clear cell Renal Cell Carcinoma

   Författare :Emma Andersson-Evelönn; Sofie Degerman; Magnus Hultdin; Göran Roos; Börje Ljungberg; Ralph Peeker; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clear cell renal cell carcinoma; DNA methylation; Prognosis; Clinical outcome; Epigenetic classifiers;

   Sammanfattning : Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell carcinoma worldwide. Metastatic ccRCC is correlated to poor prognosis whereas non-metastatic disease has a 5-year survival rate up to 90%. LÄS MER

7. 20. Mild Traumatic Brain Injury : Studies on outcome and prognostic factors

   Författare :Marianne Lannsjö; Jörgen Borg; Per Enblad; Ulla Johansson; Richard Levi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rehabilitation; Mild Traumatic Brain Injury; Rivermead Post-concussion Symptoms Questionnaire; Rasch-analysis; prediction; outcome; head CT pathology; Magnet Resonance Imaging; Rehabilitation Medicine; Rehabiliteringsmedicin;

   Sammanfattning : Objectives: To explore the prevalence and structure of self-reported disability after mild traumatic brain injury and the impact of traumatic brain pathology on such outcome.Material and methods: In study 1-3, symptoms data were collected by use of Rivermead Post-concussion Symptoms Questionnaire (RPQ) and data on global function by use of Glasgow Outcome Scale Extended (GOSE) from 2602 patients at 3 months after MTBI. LÄS MER