Sökning: "perinatal rat"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden perinatal rat.

  1. 1. Essential fatty acids in the perinatal period. Short and long term effects in a rat model

    Författare :Marina Korotkova; Göteborgs universitet; []
    Nyckelord :EFA; perinatal period; lactation; diet; adipose tissue; leptin; programming;

    Sammanfattning : Nutritional factors during a sensitive perinatal period may lead to developmental adaptations proposed to program for pathological conditions later in life. An adequate supply of essential fatty acids (EFA) during pregnancy and lactation is crucial for optimal fetal and postnatal development. LÄS MER

  3. 2. Water transport through perinatal skin : Barrier function and aquaporin water channels

    Författare :Johan Ågren; Gunnar Sedin; Gunnar Flemström; Steven B Hoath; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; Preterm infant; Transepidermal water loss; Aquaporin; Skin biology; Hyperosmolarity; Pediatrik; Paediatric medicine; Pediatrisk medicin; pediatrik; Pediatrics;

    Sammanfattning : While constituting a well functioning interface with the aqueous environment in utero, the skin offers a poor barrier after very preterm birth. As a result, transepidermal water loss (TEWL) is high, a fact which has important clinical consequences in these infants. LÄS MER

  4. 3. Perinatal programming and neuroendocrine function

    Författare :Cecilia Nilsson; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Perinatal growth and development are dependent on a sufficient metabolic, hormonal and nutritional environment. Suboptimal conditions during specific perinatal developmental windows can lead to permanent programming of physiological systems in the fetus or newborn, with implications for adult health. LÄS MER

  5. 4. Aspects of pathological apoptosis in the immature brain after hypoxia-ischemia

    Författare :Ulrika Hallin; Göteborgs universitet; []
    Nyckelord :neonatal; rat; brain; hypoxia-ischemia; necrosis; apoptosis; calpain; caspase; Bcl-2; Bax; mitochondria; calcineurin.;

    Sammanfattning : The cause of mechanisms underlying perinatal brain injury is not fully known, but it results in a wide variety of neurological impairments in the affected children. When injured, neurons of the newborn brain are prone to undergo programmed cell death, apoptosis, since this genetic program is normally activated in some cells during development of the nervous system, even in the perinatal period. LÄS MER

  7. 5. Dopamine receptors in the rat brain

    Författare :Mi Hillefors-Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dopamine D2 receptors; Dopamine D3 receptors; Rat; Autoradiography; [3H]7-OH-DPAT; [3H]PD 128907; Caudate-putamen; Subcortical limbic area; Islands of Calleja; CGS 21680; Toluene; Neurotensin; Asphyxia; Aging; Magnesium; GTP;

    Sammanfattning : Dopamine receptors belong to a large superfamily of G protein-coupled receptors and consist of the D1, D2, D3, D4, and D5 receptors. The D2, D3, and D4 receptors belong to the D2 receptor family which is characterized by having a large third cytoplasmic loop and a short C-terminus projecting into the cytosol, and by inhibiting the enzyme adenylyl cyclase. LÄS MER