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Visar resultat 11 - 15 av 267 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. Retinal pigment epithelial cells, oxidative stress and lipofuscin : relation to age-related macular degeneration

    Författare :Staffan Sundelin; Stefan Seregard; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : In developed countries, age-related macular degeneration (AMD) is the most common cause of loss of central vision in people over the age of 65. The retinal pigment epithelium (RPE) appears to be the site of early pathological changes in AMD. LÄS MER

  3. 12. Hydrolytic and Oxidative Mechanisms Involved in Cellulose Degradation

    Författare :Anu Nutt; Jerry Ståhlberg; Henrik Stålbrand; Uppsala universitet; []
    Nyckelord :Biochemistry; cellobiohydrolase; cellulase; cellulose; cellobiose dehydrogenase; endoglucanase; kinetics; synergism; competitive binding; Biokemi;

    Sammanfattning : The enzymatic degradation of cellulose is an important process in nature. This thesis has focused on the degradation of cellulose by enzymes from two cellulose-degrading fungi, Hypocrea jecorina and Phanerochaete chrysosporium, including both the action of the individual enzymes and their synergistic interplay. LÄS MER

  4. 13. Altered gene expression in the human airways during oxidative stress

    Författare :Tiziana Dandrea; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nitrogen dioxide; Ozone; Oxidative stress; Gene expression; Redox signalling; GSH; Alveolar macrophages.;

    Sammanfattning : The atmospheric accumulation of pollutant gases, such as N02 and ozone, has been associated with an increased airways hyper-reactivity within the healthy population. Moreover, those with conditions such as asthma and chronic obstructive pulmonary diseases generally experience an exacerbation of their symptoms upon exposure to these noxious gases. LÄS MER

  5. 14. Oxidative stress and muscle weakness associated with rheumatoid arthritis

    Författare :Maarten Michiel Steinz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Muscle weakness is a common comorbidity of several severe diseases which results in a reduced independence and quality of life and for the afflicted patients. For instance, patients with rheumatoid arthritis (RA), a disease characterized by a chronic inflammation of the joints, commonly report of muscle weakness as a complication. LÄS MER

  7. 15. Genetic variation and regulation of oxidative stress related genes

    Författare :Lena Forsberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Oxidative stress, is a state that has been implicated in the pathogenesis of a variety of human diseases, including atherosclerosis, inflammation, neurodegenerative disease and cancer. In an effort to determine the importance of oxidative stress in disease etiology, by a genetic approach, we have, studied individual variation and regulation of oxidative stress related genes including also basal characterization. LÄS MER