Sökning: "olfactory epithelium"

Visar resultat 11 - 13 av 13 avhandlingar innehållade orden olfactory epithelium.

  1. 11. Models for the Transfer of Drugs from the Nasal Cavity to the Central Nervous System

    Författare :Björn Jansson; Erik Björk; Sveinbjörn Gizurarson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopharmacy; Administration; intranasal; Nasal mucosa; Central nervous system; Olfactory bulb; Rat; Mouse; Swine; Cattle; Diffusion chambers; culture; In vitro; Biological models; Biological transport; Dextrans; Dopamine; Gels; Polysaccharides; Autoradiography; Fluorescence microscopy; Biofarmaci; Biopharmacy; Biofarmaci;

    Sammanfattning : The blood-brain barrier restricts the access of many compounds, including therapeutic agents, to the brain. Several human studies indicate that nasal administration of hydrophilic compounds, such as peptides, can bypass the blood-brain barrier. The aims of this thesis were to develop and refine models for this direct nose-to-brain transfer. LÄS MER

  2. 12. Seasonal variations in general activity, behaviour and cutaneous glandular structures in reindeer (Rangifer tarandus L.)

    Författare :Torgny Mossing; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Androgen; Cervidae; dermal glands; locomotor activity olfactory communicatiorL pheromones; photoperiod; rein deer; rut; seasonal variations;

    Sammanfattning : The locomotor activity of the reindeer is separated into a diurnal and a nocturnal phase which, in turn, consists of a  number of short-term activity bursts. The onset and termination  of diurnal and nocturnal activity are largely in synchrony  with sunrise and sunset. LÄS MER

  3. 13. Expression of cathelicidin antimicrobial peptides in man and rat

    Författare :Stefan Termén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :LL-37; rCRAMP; butyrate; colonic epithelium; central nervous system; transcription;

    Sammanfattning : Endogenous antimicrobial peptides are effectors of innate immunity. They kill microorganisms by disrupting their cell membranes, but are also believed to have signaling functions in the immune system. They are present in epithelia, secretions and phagocytic cells. LÄS MER