Sökning: "non-classical monocytes"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden non-classical monocytes.
1. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy
Sammanfattning : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. LÄS MER
2. Monocytes and macrophages, with a focus of Crohn's disease
Sammanfattning : Monocytes and macrophages are part of the body’s first line of defense, eliminating pathogens by phagocytosis or by releasing a broad array of inflammatory mediators, such as cytokines, chemokines and proteases. In humans, three subsets of monocytes are described with seemingly different functions. LÄS MER
3. Immunological effects of isolated regional perfusion in malignant melanoma
Sammanfattning : Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables much higher tissue concentrations of the chemotherapeutic agent compared with systemic administration. LÄS MER
4. Origin and ontogeny of human lung macrophages
Sammanfattning : The lung is a vital organ occupied by a large diversity of immune cells due to its close proximity with the external environment. This thesis focuses on a particular type of immune cell: the macrophage. LÄS MER
5. Studies on myeloid cell functions in periodontitis
Sammanfattning : Periodontitis (PD) is a chronic inflammatory disease characterized by destruction of the tooth supporting tissues; gingiva, periodontal ligament, and alveolar bone. Myeloid cells, including monocytes and macrophages, play a crucial part in the inflammatory host response by clearing pathogens and producing a vast array of inflammatory mediators. LÄS MER