Sökning: "Gene-expression"

Visar resultat 1 - 5 av 2112 avhandlingar innehållade ordet Gene-expression.

1. 1. Statistical analysis of gene expression data

   Författare :Erik Kristiansson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene expression; DNA microarrays; linear models; empirical Bayes; quality control; gene regulation; categorical data analysis; logistic regression; heavy metal stress; ecotoxicology; gene expression;

   Sammanfattning : Microarray technology has become one of the most important tools for genome-wide mRNA measurements. The technique has been successfully applied to many areas in modern biology including cancer research, identification of drug targets, and categorization of genes involved in the cell cycle. LÄS MER

3. 2. Gene expression in carcinogenesis

   Författare :Heléne Fischer; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. LÄS MER

4. 3. Nonlinear dimensionality reduction of gene expression data

   Författare :Jens Nilsson; Matematik LTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gene expression; Manifold learning; Nonlinear dimensionality reduction; Microarray;

   Sammanfattning : Using microarray measurements techniques, it is possible to measure the activity of genes simultaneously across the whole genome. Since genes influence each others activity levels through complex regulatory networks, such gene expression measurements are state samples of a dynamical system. LÄS MER

5. 4. Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis

   Författare :Kirsten Kehrein; Martin Ott; Thomas A Fox; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; Biochemistry; biokemi;

   Sammanfattning : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. LÄS MER

7. 5. Deconvolution of Spatial Gene Expression in Cancer

   Författare :Linnea Stenbeck; Stefania Giacomello; Joakim Lundeberg; Vicent Pelechano; KTH; []
   Nyckelord :Spatial transcriptomics; Gene expression; Cancer; Bioteknologi; Biotechnology;

   Sammanfattning : Cancer is the second leading cause of death in the world, claiming nearly 10 million lives in 2020 alone. One of the main issues in anti-cancer treatment is the heterogeneity of the tumor microenvironment (TME). The TME consists of different cells that are critical for cancer development. LÄS MER