Sökning: "nitrone"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet nitrone.

  1. 1. Stereoselectivity in organic chemistry : asymmetric 1,3-dipolar cycloadditions and rule-based conformational analysis

    Författare :Kaye Stern; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molecular mechanics; nitrile oxides; Stereochemistry; nitrone;

    Sammanfattning : .... LÄS MER

  3. 2. The role of reactive oxygen species in traumatic brain injury : Experimental studies in the rat

    Författare :Niklas Marklund; Uppsala universitet; []
    Nyckelord :Medical sciences; Apoptosis; CBF; controlled cortical contusion injury; 3; 4-dihydroxybenzoate; fluid percussion injury; glucose; 4-hydroxybenzoate; microdialysis; Morris Water Maze; neuroprotection; nitrones; PBN; rat; reactive oxygen species ROS ; salicylate; S-PBN; TBI; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Neurosurgery; neurokirurgi;

    Sammanfattning : Traumatic brain injury (TBI) is a major cause of mortality and disability. As common sequelae in survivors of TBI are disabling functional, emotional and cognitive disturbances, improved treatment of TBI patients is urgently needed. At present, no neuroprotective pharmacological treatment exists. LÄS MER

  4. 3. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

    Författare :Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. LÄS MER

  5. 4. Resolution of Dynamic Systems: Applications in Asymmetric Synthesis and Materials Science

    Författare :Lei Hu; Olof Ramström; Douglas Philp; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry;

    Sammanfattning : This thesis is built on the concepts of constitutional dynamic chemistry and dynamic kinetic resolution, where reversible covalent reactions are used to generate dynamics and kinetically controlled reactions are employed for resolution. The thesis is divided into two parts:The first section focuses on the study of dynamic systemic resolution, a concept derived from constitutional dynamic chemistry. LÄS MER

  7. 5. Neurogenesis, neural stem cells and nitric oxide in neuroinflammation

    Författare :Alexandre I Danilov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurogenesis; neuronal stem cells; nitric oxide; Multiple Sclerosis; EAE; brain trauma;

    Sammanfattning : We investigated whether nitric oxide (NO) is produced in MS patients, determining the concentrations of its oxidation products (NOx) in CSF. The total levels of NOx in CSF were significantly increased in all MS groups as compared to healthy controls and tension headache patients. LÄS MER