Sökning: "mouse development"
Visar resultat 16 - 20 av 1047 avhandlingar innehållade orden mouse development.
16. Epigenetic Control of Mammalian Development : Studies on an imprinting control region
Sammanfattning : A subset of autosomal genes is preferentially or exclusively expressed from one of the parental alleles. This phenomenon, termed genomic imprinting, is highlighted by the neighboring Igf2 and H19 genes, which are monoallelically expressed on opposite parental chromosomes. These features are governed by a 2. LÄS MER
17. Molecular specification of expanded forebrain neural stem and progenitor cells
Sammanfattning : The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. LÄS MER
18. The role of PDGF-A in lung development, injury and repair
Sammanfattning : The developmental processes that take place during embryogenesis depend on a great number of proteins that are important for cell-to-cell communication. Platelet-derived growth factors are known to be important for epithelial-mesenchymal interactions during development and organogenesis. LÄS MER
19. The Role of the SHB Adapter Protein in Cell Differentiation and Development
Sammanfattning : The present study was conducted in order to assess a role of the SH2 domain-containing adapter protein SHB in development and cell differentiation.Embryonic stem (ES) cells overexpressing SHB and SHB with an inactive SH2 domain (R522K-SHB) were obtained. LÄS MER
20. A-to-I RNA editing : Function and consequences during brain development
Sammanfattning : The aim of my thesis has been to study how A-to-I RNA editing of miRNAs is regulated during brain development and the biological function of these editing events.Using high throughput RNA sequencing, we performed an unbiased search for edited, mature miRNAs in total mouse brain tissue from three developmental stages. LÄS MER