Sökning: "in vitro expansion"
Visar resultat 1 - 5 av 141 avhandlingar innehållade orden in vitro expansion.
1. Biodegradable gelatin microcarriers in tissue engineering : In vitro studies on cartilage and bone
Sammanfattning : Tissue engineering is a multidisciplinary field that combines cells, biomaterial scaffolds and environmental factors to achieve functional tissue repair. This thesis focuses on the use of macroporous gelatin microcarriers as scaffolds in tissue engineering applications, with a special focus on cartilage and bone formation by human adult cells in vitro. LÄS MER
2. Molecular mechanisms in lymphoid restriction : securing the B lineage fate
Sammanfattning : With the work in this thesis I have aimed to deepen the understanding of the mechanisms behind the development of different blood cell lineages with a specific focus on B cell development.To understand the interplay between extracellular signaling and transcription factor networks in early lymphoid development we investigated the functional collaborations of FLT3 and IL7R. LÄS MER
3. Urothelial cell culturing : in vitro and in vivo studies in reconstructive pediatric surgery
Sammanfattning : In Pediatric Surgery many malformations present underdevelopment of tissues and organs. When surgical treatment is needed, the reconstruction can sometimes be restricted because of shortage of tissue for the repair. LÄS MER
4. Human embryonic stem cells for bone engineering applications
Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER
5. Preparatory Studies to Introduce Regulatory T Cells in Clinical Transplantation
Sammanfattning : Solid organ transplantation has evolved from being an experimental procedure to a life-saving treatment for patients with end-stage organ failure. The risk of losing a transplant due to acute rejection is very low with the use of modern immunosuppressive protocols and the short-term results are impressive. LÄS MER