Sökning: "molekylär evolution"

Visar resultat 26 - 30 av 125 avhandlingar innehållade orden molekylär evolution.

  1. 26. Unique Solutions to Universal Problems : Studies of the Archaeal Cell

    Författare :Erik A. Pelve; Rolf Bernander; Sonja Verena Albers; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Archaea; Cdv; Cell cycle; Cell division; Cell lysis; Crenarchaea; ESCRT-III; Flow cytometry; Microarray; Microscopy; Nitrosopumilus; SIRV2; Sulfolobus; Thaumarchaea; Transcription; VAP; Virus; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Sammanfattning : Archaea is one of the three domains of life and studies of archaeal biology are important for understanding of life in extreme environments, fundamental biogeochemical processes, the origin of life, the eukaryotic cell and their own, unique biology. This thesis presents four studies of the archaeal cell, using the extremophilic Sulfolobus and ocean living Nitrosopumilus as model systems. LÄS MER

  3. 27. Adaptive Evolution of the Bacterial Translation Machinery

    Författare :Arindam De Tarafder; Suparna Sanyal; Michael Y. Pavlov; Ruben L. Jr. Gonzalez; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Translation; Translation machinery; Elongation; Evolution; RNA world; Cold bacteria; Molekylär biovetenskap; Molecular Life Sciences;

    Sammanfattning : The process of protein synthesis via translation is of paramount importance for the existence of life on Earth. The bacterial translation machinery has embraced more than 3.5 billion years of molecular evolution to adapt and function efficiently under the provided physiological conditions. LÄS MER

  4. 28. Plant Major Intrinsic Proteins - natural variation and evolution

    Författare :Jonas Danielson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MIP; aquaporin; plant; natural variation; evolution; Arabidopsis; Physcomitrella patens; NIP; XIP;

    Sammanfattning : Major Intrinsic Proteins (MIPs, also called Aquaporins, AQPs) are channel forming membrane proteins. Although initially functionally characterized and named after their water channeling property in human red blood cells, it has become increasingly evident that MIPs are present in all types of organisms and transport a variety of small, uncharged molecules besides water. LÄS MER

  5. 29. Ribosome display for selection and evolution of affibody molecules

    Författare :Sebastian Grimm; Per-Åke Nygren; Mike Taussig; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; ribosome display; phage display; combinatorial protein engineering; library; murine IgG1; SATB1; Ras; Raf; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Affinity proteins are invaluable tools in biotechnological and medical applications. This thesis is about combinatorial protein engineering principles for the generation of novel affinity proteins to purify mouse immunoglobulin, detect a potential cancer marker protein or inhibit a cell proliferation pathway. LÄS MER

  7. 30. Comparative analysis of the thermogenic protein UCP1 across the mammalian phylogeny

    Författare :Michael James Gaudry; Martin Jastroch; Tobias Wang; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Uncoupling protein 1; Evolution; Non-shivering thermogenesis; Brown adipose tissue; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Uncoupling protein 1 (UCP1) drives mitochondrial inefficiency to produce heat in mammalian brown adipose tissue (BAT). Many mammalian species rely on this form of adaptive non-shivering thermogenesis (NST) to defend high body temperatures in the cold. LÄS MER