Sökning: "molecular weight distribution"

Visar resultat 26 - 30 av 91 avhandlingar innehållade orden molecular weight distribution.

  1. 26. Linear and Branched Chitosan Oligomers as Delivery Systems for pDNA and siRNA In Vitro and In Vivo

    Författare :Mohamed Mahmoud Issa; Per Artursson; Arto Urtti; Uppsala universitet; []
    Nyckelord :Medical sciences; Chitosan oligomers; gene delivery; gene expression; pDNA; siRNA; MEDICIN OCH VÅRD;

    Sammanfattning : In this thesis, chitosan, a biocompatible polysaccharide that has been approved as a food additive was selected as a platform for the development of safe, efficient non-viral gene delivery systems to mammalian cells. Previously, chitosan-based gene formulations had been generally associated with high molecular weight chitosans, which were poorly characterised in terms of molecular weight distribution and degree of acetylation. LÄS MER

  3. 27. Design of polyester and porous scaffolds

    Författare :Karin Odelius; Ann-Christine Albertsson; Monica Ek; Torbjörn Mathisen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ring-opening polymerization; porous scaffold; L-lactide; 5-dioxepane-2-one; ε-caprolactone; spirocyclic initiator; star-shaped polyester; Polymer chemistry; Polymerkemi;

    Sammanfattning : The use of synthetic materials for tissue and organ reconstruction, i. e. tissue engineering, has become a promising alternative to current surgical therapies and may overcome the shortcomings of the methods in use today. LÄS MER

  4. 28. Influence of processing and processing additives on the degradation of aliphatic polyesters

    Författare :Rasmus Renstad; KTH; []
    Nyckelord :;

    Sammanfattning : Poly(3-hydroxybutyrate-co-3-hydroxyvalerate), P(3HB-co-3HV),poly(ε-caprolactone), PCL, and poly(lactic acid), PLA,have been subjected to film-blowing, melt-extrusion andmelt-pressing. The influence of processing conditions andprocessing additives (i.e. plasticizer, antiblocking and slipagents) on properties and degradation have been studied. LÄS MER

  5. 29. New biodegradable polymers from renewable resources

    Författare :Yan Liu; KTH; []
    Nyckelord :;

    Sammanfattning : High molecular weight poly(ester-carbonate)s have beenprepared by a two-step chain-extension reaction performed onoligomeric αω-bishydroxyl-terminatedpoly(1,3-propylene succinate).αω-Bishydroxyl-terminated copolymeric oligomers of1,3-propylene succinate/1,4-cyclohexanedimethylene succinatewere obtained by thermal polycondensation of1,3-propanediol/1,4-cyclohexanedimethanol/succinic acidmixtures having different composition, and subsequently chainextended using phosgene as coupling agent, which leads toaliphatic/alicyclic copoly(ester-carbonate)s. LÄS MER

  7. 30. Studies on a novel cytosolic/nuclear binding protein for the eicosanoid 12(S)-hydroxyeicosatetraenoic acid

    Författare :Helena Herbertsson; Örjan Wrange; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Hydroxyeicosatetraenoic acids (HETEs) are lipoxygenase metabolites of arachidonic acid. HETEs were long considered to have few or no important biological function - a view that proved to be incorrect. LÄS MER