Sökning: "mechanistic modeling"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden mechanistic modeling.

  1. 1. Mechanistic-Empirical Modeling of Permanent Deformation in Asphalt Concrete Layers

    Detta är en avhandling från Department of Technology and Society, Lund University

    Författare :Erik Oscarsson; [2011]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; permanent deformation; modeling; Mechanistic-Empirical; rutting; asphalt concrete; full-scale pavements;

    Sammanfattning : Three mechanistic-empirical permanent deformation models were evaluated under Swedish conditions with respect to traffic, climate and materials using accelerated pavement testing and long-term pavement performance studies. The mechanistic-empirical pavement design guide (M E PDG), the incremental-recursive mechanistic-empirical CalME model (CalME), and the PErmanent Deformation of asphalt concrete layer for ROads (PEDRO) model generally showed both useful features and limitations. LÄS MER

  2. 2. Monitoring of product variants in biopharmaceutical downstream processing Mechanistic and data-driven modeling approaches

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Patricia Roch; Linköpings universitet.; Linköpings universitet.; [2019]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : During the manufacturing of biopharmaceuticals, a multistep purification strategy is employed to remove process-related impurities and product variants, to achieve high product quality, assuring patients’ safety. To guarantee that biopharmaceuticals are safe and to accomplish quality, strict policies were established by regulatory agencies as well as guiding principles, such as Quality by Design and process analytical technology. LÄS MER

  3. 3. Predictive Modeling of Lake Eutrophication

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jan Mikael Malmaeus; Uppsala universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Earth sciences; mass balance model; dynamic model; mechanistic model; phosphorus; LEEDS; suspended particulate matter; settling velocity; sedimentation; accumulation sediments; burial; diffusion; climate scenario; Erken; Balaton; Kinneret; Batorino; Miastro; Naroch; Galten; Ekoln; Geovetenskap; NATURAL SCIENCES Earth sciences; NATURVETENSKAP Geovetenskap;

    Sammanfattning : This thesis presents predictive models for important variables concerning eutrophication effects in lakes. The keystone is a dynamic phosphorus model based on ordinary differential equations. LÄS MER

  4. 4. Modeling and Optimization of Reversed-Phase Chromatography : Effects of Modulators and Temperature

    Detta är en avhandling från Department of Chemical Engineering, Lund University

    Författare :Karolina Arkell; Lund University.; Lunds universitet.; [2017]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Reversed-phase chromatography; Hydrophobic interaction chromatography; Mechanistic modeling; INSULIN; KCl; Ethanol; Temperature; Multi-objective optimization; Constraint; Solubility;

    Sammanfattning : Many widespread diseases, such as diabetes, various types of cancer, and aggressive versions of influenza, are treated or prevented with biopharmaceuticals. Biopharmaceuticals are drugs that are based on proteins, peptides, antibodies, attenuated viruses (vaccines), and other biomolecules that are synthesized predominately in bacteria, yeast, and mammalian cells. LÄS MER

  5. 5. Biomimetic Transition Metal Catalysts : Insights from Theoretical Modeling

    Detta är en avhandling från Stockholm : Fysikum

    Författare :Adam Johannes Johansson; Stockholms universitet.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; biomimetic; copper; non-heme iron; heme iron; O2 cleavage; H-atom transfer; radical chemistry; redox chemistry; thermo chemistry; entropy calculations; quantum chemistry; spin states; density functional theory DFT ; self-interaction error SIE .; NATURAL SCIENCES Physics Atomic and molecular physics Chemical physics; NATURVETENSKAP Fysik Atom- och molekylfysik Kemisk fysik; Chemical Physics; kemisk fysik;

    Sammanfattning : The scientific interest in the chemistry of synthetic transition metal complexes is motivated by at least two arguments:1.These can be regarded as models of biological transition metal complexes, e.g. metalloenzymes, whose functions can be difficult to reveal in detail due to their complexity. LÄS MER