Sökning: "master thesis"

Visar resultat 11 - 15 av 400 avhandlingar innehållade orden master thesis.

  1. 11. Multiscale Stochastic Simulation of Reaction-Transport Processes : Applications in Molecular Systems Biology

    Författare :Andreas Hellander; Per Lötstedt; Sverker Holmgren; Samuel Isaacson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; stochastic simulation; chemical master equation; reaction-diffusion master equation; unstructured mesh; active transport; hybrid methods; URDME; Scientific Computing; Beräkningsvetenskap;

    Sammanfattning : Quantitative descriptions of reaction kinetics formulated at the stochastic mesoscopic level are frequently used to study various aspects of regulation and control in models of cellular control systems. For this type of systems, numerical simulation offers a variety of challenges caused by the high dimensionality of the problem and the multiscale properties often displayed by the biochemical model. LÄS MER

  3. 12. Downstream effects of master regulators in two brain diseases

    Författare :Sebastian Braun; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rett syndrome; brain tumor development; gene regulation; neural stem cells; cell of origin; BMI1;

    Sammanfattning : In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in comparison to untreated mutant and to treated and untreated wild-type animals. LÄS MER

  4. 13. Cell-matrix interactions : master regulators of cancer cell fate?

    Författare :Sara Göransson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development and homeostasis of a multicellular organism require fundamental biological processes like cell proliferation, cell differentiation, cell migration, and controlled cell death. The extracellular matrix (ECM) guides many of these functions, via cell-matrix interactions that function as mechanical and biochemical signaling hubs. LÄS MER

  5. 14. Testing palaeomagnetic and 14C based geochronological methods in the Baltic Sea

    Författare :Bryan Lougheed; Kvartärgeologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Baltic Sea; coastal; geochronology; palaeomagnetic secular variation; PSV; radiocarbon; 14C; reservoir age; R t ; ΔR; salinity; δ18O; geomagnetic field; Holocene; deglacial; Fennoscandia.;

    Sammanfattning : The Baltic Sea is a continental shelf sea that is influenced by both river runoff and marine water. The two water masses are vertically stratified in the Baltic Sea, resulting in a positive, estuarine circulation system, which has undergone changes in the past due to isostatic uplift of the Baltic basin. LÄS MER

  7. 15. Processing Methods for Reaching Full Density Powder Metallurgical Materials

    Författare :Maheswaran Vattur Sundaram; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; gas atomised powder; water atomised powder; high density powder metallurgical materials; high density; master alloys; liquid phase sintering; sintering; high velocity compaction; hot isostatic pressing; additive manufacturing;

    Sammanfattning : Powder metallurgy (PM) is one of the most cost effective methods for manufacturing structural components with complex shapes. Utilisation of the metal powder to shape the components allows to minimise material waste and increase energy efficiency. LÄS MER