Sökning: "lymphocyte stimulation"

Visar resultat 6 - 10 av 64 avhandlingar innehållade orden lymphocyte stimulation.

  1. 6. Innate lymphocyte responses in inflammatory diseases

    Författare :Johanna Emgård; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immune system is a highly sophisticated system that has evolved to protect the host from external and internal threats. However, under some circumstances the immune response can get dysregulated and cause inflammatory diseases. LÄS MER

  3. 7. The B lymphocyte in Staphylococcus aureus arthritis

    Författare :Inger Gjertsson; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; mice; arthritis; sepsis; B cells; Fcg receptors; CD22; ; IL-4; IL-10; IFN-g.;

    Sammanfattning : Joint infection caused by Staphylococcus aureus leads to heavy synovitis and rapid destruction of bone and cartilage. Permanent loss of joint function is seen in 20-50% of the patients, despite early eradication of the bacteria with antibiotics. LÄS MER

  4. 8. Human cytotoxic lymphocyte differentiation in health and disease

    Författare :Heinrich Schlums; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytotoxic lymphocytes, comprising natural killer (NK) cells and CD8+ cytotoxic T cells, eradicate infected or malignant cells by release of lytic granules and alarm the immune system through production of pro-inflammatory cytokines and chemokines. NK cells and CD8+ T cells belong to different arms of the immune system, employing complementary strategies for target cell recognition. LÄS MER

  5. 9. Development of the gastrointestinal tract in young mammals : Effects of enteral provocation with protease or phytohaemagglutinin in neonatal rats

    Författare :Ester Arevalo Sureda; Funktionell zoologi; []
    Nyckelord :gut; Intestine; Pancreas; development; precocious; protease; PHA; enterocytes; permeability; endocytosis; IgG; FcRn; Blimp1; T-lymphocyte; passive immunity; altricial; neonatal; suckling; athymic; rat; immunohistochemistry IHC ;

    Sammanfattning : The rat, as an altritial species, is born with an immature gastrointestinal tract and intestinal barrier function, which is highly absorptive to milk-borne bioactive molecules that can pass undigested and reach the general circulation of the suckling newborn. This passage occurs by the neonatal-Fc-receptor (FcRn) binding and trancytosis of immunoglobulin G in the proximal small intestine (SI) and by the highly endocytic vacuolated enterocytes non-selectively in the distal SI. LÄS MER

  7. 10. Aspects of interferon alpha signalling in hematopoetic cells

    Författare :Lennart Carlsson; erik lundgren; Ulrich Kalinke; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; interferon; human; B-lymphocyte; survival; proliferation; myeloma; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The type I interferons (IFN) are a family of cytokines with pleiothropic activities that include inhibition of viral replication, cell proliferation and activation of the immune system. These properties give the IFNs important physiological and pathological roles in infection and cancer and have led to their therapeutic use for many clinical conditions. LÄS MER