Sökning: "lymphocyte stimulation"

Visar resultat 16 - 20 av 64 avhandlingar innehållade orden lymphocyte stimulation.

  1. 16. Involvement of T lymphocyte subsets in the rejection of murine tumors by syngeneic or autologous hosts

    Författare :Tao Wen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis is to study the requirement of CD4+ and CD8+ T Iymphocyte subset, CD28 costimulatory molecule and p56kk for the rejection of syngeneic tumor grafts, and the autochthonous tumors induced by Moloney murine sarcoma virus. It also addresses the role of CD4+ and CD8+ T subsets with regard to the polyomavirus persistence and tumor development. LÄS MER

  3. 17. Butyrophilin- and Butyrophilin-like genes and their role in epithelial cell-intraepithelial T lymphocyte cross-talk

    Författare :Cristina Lebrero-Fernandez; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Butyrophilin-like Btnl ; Butyrophilin Btn ; Intraepithelial lymphocytes IELs ; Mucosal immunity; Intestinal epithelial cells; γδ T cells; Intestinal inflammation; Colon cancer; Ulcerative colitis;

    Sammanfattning : More than 50% of our immune system is located in the gut. The intestinal epithelium, which forms an interface between the organism and the environment, harbors intraepithelial lymphocytes (IELs) that comprise a mixture of conventional αβ T cells and unconventional αβ- and γδ T cells. LÄS MER

  4. 18. Studies on stress in African green monkeys (Cercopithecus aethiops) : Stress associated cortisol and prolactin levels, lymphocyte modulation and pathological changes in adrenal cortex, stomach and hippocampus in the African green monkey (C. aethiops)

    Författare :Mbaruk Abdalla Suleman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; adrenal cortex; capture; confinement; cortisol; husbandry; housing; hippocampus; lymphocytes; prolactin; stomach; stress; wild; African green monkeys; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : African green monkeys (AGMs) are highly susceptible to captivity-induced stress. An investigation of spontaneous deaths of laboratory confined AGMs at the Institute of Primate Research, Nairobi, Kenya over a period of 7.5 years documented mild to severe gastric mucosal erosions and ulcers in 83 of 260 (32%) necropsies. LÄS MER

  5. 19. Preclinical therapeutic vaccination strategies in malignancies with focus on B-cell chronic lymphocytic leukemia

    Författare :Parviz Kokhaei; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunotherapy; dendritic cells. chronic lymphocytic leukemia; tumor vaccine; T lymphocyte;

    Sammanfattning : A therapeutic strategy that may potentially delay progression or prevent relapse of B-cell chronic lymphocytic leukemia (B-CLL), is anti-leukemic vaccine therapy. This thesis focuses on comparing different strategies for loading antigen on dendritic cells (DC) with the aim of delineating the most effective antigen presentation platform for stimulating anti-leukemic T cells. LÄS MER

  7. 20. Characterisation of human fetal mesenchymal stem cells

    Författare :Cecilia Götherström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mesenchymal stem cells; fetal stem cell transplantation; intrauterine transplantation; osteogenesis imperfecta; mixed lymphocyte culture; gene array;

    Sammanfattning : Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared to adult bone marrow-derived MSCs. LÄS MER