Sökning: "lungfibros"

Hittade 5 avhandlingar innehållade ordet lungfibros.

  1. 1. Systemic sclerosis. Novel molecular and epidemiological features of disease

    Författare :Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

    Sammanfattning : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. LÄS MER

  3. 2. Autoantibody profiling in autoimmune diseases

    Författare :Shaghayegh Bayati; Peter Nilsson; Elisa Pin; Peter Heeringa; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; Autoantibodies; Vasculitis; Systemic Sclerosis; affinity proteomics; Biotechnology; Bioteknologi;

    Sammanfattning : Autoimmune disease diagnosis and definition of prognosis can be challenging. Patients with the same autoimmune disease could present with very heterogeneous symptoms. Therefore, there is a need to understand the disease better to improve patients’ diagnosis, and classification, and tailor the treatment. LÄS MER

  4. 3. Biglycan as a modulator of fibrous connective tissue

    Författare :Ellen Tufvesson; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biglycan decorin fibroblast interleukin-1beta migration proteoglycan structure tumour necrosis factor-alpha; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Fibrous connective tissue contains fibroblasts distributed in a complex network of extracellular matrix molecules, such as proteoglycans. The small proteoglycans biglycan and decorin are composed of a protein core substituted with two and one glycosaminoglycan (GAG) chain, respectively. LÄS MER

  5. 4. Airway mechanics of mice and men

    Författare :Lennart Lundblad; Malmö Klinisk fysiologi och nuklearmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; radiologi; tomografi; tomography; medical instrumentation; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; Penh; emphysema; airway resistance; gas conditioning; plethysmography; lung mechanics; Boyle s law; Physiology; medicinsk instrumentering; Klinisk fysiologi; radiology; enhanced pause; pulmonary fibrosis; micro computed tomography; forced oscillation technique; COPD;

    Sammanfattning : In this thesis we explore and further develop several techniques used in the animal laboratory as well as in the clinical setting. In particular, we expand the understanding and usefulness of plethysmographic techniques in small rodents. LÄS MER

  7. 5. Proteinase 3 and Neutrophil Apoptosis in ANCA-Associated Systemic Vasculitis

    Författare :Mohamed AbdGawad; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener’s granulomatosis; anti-neutrophil cytoplasmic antibody ANCA . Proteinase 3 PR3 ; myeloperoxidase MPO . Flowcytometry FACS . Vasculitis.; microscopic polyangitis;

    Sammanfattning : ANCA-Associated Systemic Vasculitis (AASV) is characterized by leukocytoclasis- dying neutrophils surrounding small blood vessels. Previous studies have shown increased plasma PR3 and increased proportion of neutrophils expressing plasma membrane-associated PR3 (mPR3+). LÄS MER