Sökning: "lokal anestesi"

Hittade 5 avhandlingar innehållade orden lokal anestesi.

  1. 1. Bioelectronic Devices for Targeted Drug Delivery and Monitoring of Microbial Electrogenesis

    Författare :Arghyamalya Roy; Daniel T Simon; Klas Tybrandt; Christopher Proctor; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrophoresis; Extracellular Electron Transfer EET ; Ion Exchange Membranes IEM ; Drug Delivery; Bupivacaine; Chronic Neuropathic Pain; Microfabrication; Inkjet Printing; Organic Electrochemical Transistor OECT ; Fumarate; Shewanella oneidensis; Dorsal Root Ganglia DRG ; Organic Electronic Ion Pump OEIP ;

    Sammanfattning : Despite a range of pain therapies available in the market, 70% of patients report so-called “breakthrough pain”. Coupled with global issues like opioid crisis, there is a clear need for advanced therapies and technologies for pain management. LÄS MER

  3. 2. Levosimendan in early experimental sepsis: effects on the heart and hepatosplanchnic circulation

    Författare :Doris Cunha Goncalves; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; septic shock; myocardial oxygen consumption; myocardial dysfunction; levosimendan; endotoxin; contractility; catecholamines; calcium sensitizer; cardiotonic agents; splanchnic perfusion;

    Sammanfattning : Sepsis-related cardiovascular dysfunction associated with fluid-unresponsive tissue hypoperfusion might require inotropic treatment. This cardiovascular dysfunction seems to involve calcium desensitization and adrenergic unresponsiveness. LÄS MER

  4. 3. Aspects of bleeding complications and hemostasis at central line insertion and mild induced hypothermia

    Författare :Thomas Kander; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Central venous catheter. Coagulation. Bleeding complications. Platelets. Mild induced hypothermia. Point of care coagulation tests. Flow cytometry.;

    Sammanfattning : Bleeding complications range from 0.5 to 1.6% in connection with central venous catheter insertions but are more frequent in patients with bone marrow failure and severe thrombocytopenia. Although supportive evidence is scarce, prophylactic platelet transfusion is sometimes performed in these patients before catheter insertion. LÄS MER

  5. 4. Microdialysis and Intensive Care. Clinical and experimental studies

    Författare :Per Ederoth; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; traumatic brain injury; glucose; glycerol; lipolysis; epidural; postoperative analgesia; experimental pancreatitis; human; blood-brain barrier; morphine; pharmacokinetics; Microdialysis; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : Microdialysis was used to monitor local concentrations of energy metabolites in different organs, and to study the pharmacokinetics of morphine over the blood-brain barrier in intact and injured brain tissue in conditions treated in the Intensive Care Unit. After major abdominal or thoracoabdominal surgery, postoperative thoracic epidural analgesia resulted in higher glycerol concentrations in the deltoid subcutaneous adipose tissue, implying increased lipolysis, on the third postoperative day as compared to intravenous infusion of morphine, possibly due to a locally increased sympathetic tone. LÄS MER

  7. 5. Prevention of intimal hyperplasia after balloon angioplasty and / or stent insertion. or How to mend a broken heart - Just say NO

    Författare :Jan Harnek; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; Remodeling. Endothelium-derived factors. Self-expanding stents. Restenosis. Scanning -electron microscopy. Endothelial factors. Nitric oxide. Intimal hyperplasia. Angioplasty. Stents. Interventional procedures. Endothelium.;

    Sammanfattning : Background: Restenosis is the most frequently occurring adverse event after percutaneous intravascular treatment of atherosclerotic lesions, which limits long-term patency of the intervention. Objective: The aim of the study was to evaluate if minimizing vascular injury during treatment by insertion of self-expanding stents or modifying the reparative mechanisms by local drug delivery can reduce restenosis. LÄS MER