Sökning: "large intestine"

Visar resultat 6 - 10 av 89 avhandlingar innehållade orden large intestine.

1. 6. Intestinal IgA synthesis: Localization and requirements for IgA class switch recombination

   Författare :Peter Bergqvist; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA; Intestine; Gut associated lymphoid tissue; class switch recombination; CD40; germ free;

   Sammanfattning : Production of IgA at mucosal surfaces is one of the most striking features of the mucosal immune system. Despite that IgA was first discovered in the 1950’s and secretory IgA described in gut secretions and breast milk in the mid 1960’s we still have limited information about the sites and exact requirements for IgA class switch recombination. LÄS MER

3. 7. EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA

   Författare :Hanna Stenstad; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; Immunology; serology; homing; intestine; GALT; chemokine receptor; lymphocyte; serologi;

   Sammanfattning : The intestinal mucosa, including the intestinal epithelium and underlying lamina propria (LP), contains a large number of effector/memory T cells that are thought to play a central role in the generation and maintenance of mucosal immune responses and in maintaining mucosal integrity. The work in this thesis investigates the mechanisms regulating effector T cell recruitment to the small intestinal mucosa focusing on the role of chemokine receptors in this process. LÄS MER

4. 8. Study of the colonic mucus layer by mass spectrometry

   Författare :Sjoerd van der Post; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MUC2; mucin; intestine; proteomics; mass spectrometry;

   Sammanfattning : The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the lower parts of the digestive tract where the microbiota reaches its highest density. LÄS MER

5. 9. Intestinal mucins 'soluble and insoluble problems'

   Författare :Annkatrin Herrmann; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal carcinoma; pulse labelling; organ culture; glycopeptide; small intestine; colon; glycoprotein complex; insoluble; muc2; MUC2; Mucin; mucus; carbohydrate; oligosaccharide.; Gastro-enterology; Gastroenterologi;

   Sammanfattning : Highly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. LÄS MER

7. 10. Colonization, persistence and virulence factors in Escherichia coli strains in the human intestinal microflora

   Författare :Forough Nowrouzian; Göteborgs universitet; []
   Nyckelord :Escherichia coli; large intestine; infant; newborn; bacterial adhesins; hemolysins;

   Sammanfattning : Escherichia coli is a member of the normal intestinal microflora of man and many animals. In this thesis, various aspects of the E. coli colonization pattern were studied, especially the role of so called virulence factors for persistence of E. coli in the gut microflora. LÄS MER