Sökning: "germ free"

Visar resultat 1 - 5 av 46 avhandlingar innehållade orden germ free.

  1. 1. Intestinal IgA synthesis: Localization and requirements for IgA class switch recombination

    Författare :Peter Bergqvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA; Intestine; Gut associated lymphoid tissue; class switch recombination; CD40; germ free;

    Sammanfattning : Production of IgA at mucosal surfaces is one of the most striking features of the mucosal immune system. Despite that IgA was first discovered in the 1950’s and secretory IgA described in gut secretions and breast milk in the mid 1960’s we still have limited information about the sites and exact requirements for IgA class switch recombination. LÄS MER

  3. 2. Influence of the microflora on gastrointestinal nitric oxide generation : studies in newborn infants and germ-free animals

    Författare :Tanja Sobko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nitrite; nitrate; IBD; lactobacilli; probiotics; germ-free; SCFA; H 2; newborn infants;

    Sammanfattning : Interactions between intestinal bacteria and the host play an important role in physiological regulation of gut function and in development of various diseases. Nitric oxide (NO) exhibits a variety of biological actions in the gut including regulation of regional blood flow, gut motility, water and electrolyte transport and immunity. LÄS MER

  4. 3. Derivation, Characterization and Differentiation of Feeder-Free Human Embryonic Stem Cells

    Författare :Narmin Bigdeli; Göteborgs universitet; []
    Nyckelord :Embryonic Stem Cells; Differentiation;

    Sammanfattning : Human embryonic stem cells (hESCs) are pluripotent cells with self-renewal ability, derived from the inner cell mass of a human blastocyst. They have the remarkable potential to develop into different cell types and can thus be used to regenerate and restore damaged tissues and organs in the entire body. LÄS MER

  5. 4. Chromatographic Studies of Solute Interactions with Immobilized Red Blood Cells and Biomembranes

    Författare :Ingo Gottschalk; Irving W. Wainer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Affinity; Binding; Biomembrane; Biotin; Chromatography; Cytochalasin B; Dissociation constant; Drug absorption; Equilibrium; Glucose; GLUT1; Immobilization; Immobilized biomembrane affinity chromatography; Immobilized liposome chromatography; Interaction; Liposome; Membrane protein; Membrane vesicle; Partitioning; Phospholipid bilayer; Proteoliposome; Quantitative; Red blood cell; Solute; Specific; Streptavidin; Wheat germ agglutinin; Biokemi; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Sammanfattning : Specific and non-specific interactions of solutes with immobilized biomembranes were studied using chromatographic methods. Liposomes, proteoliposomes and red blood cell (RBC) membrane vesicles were immobilized by a freeze-thawing procedure, whereas whole RBCs were adsorbed in the gel beds using electrostatic interaction, binding to wheat germ agglutinin (WGA) or the streptavidin-biotin interaction. LÄS MER

  7. 5. Modeling human germ cell development with pluripotent stem cells and characterizing the putative oogonial stem cells

    Författare :Sarita Panula; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The current understanding of human germ cell development is limited and is at most parts extrapolated from studies of mice or other model organisms. Particularly, the specification events of human germ cell lineage are largely unknown, which is at least in part due to inaccessibility of early stages of human development. LÄS MER