Sökning: "la antigens"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden la antigens.

1. 1. Mechanisms of lymphocyte selection in physiology and autoimmune pathology

   Författare :Stina Forsgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cell activation; la antigens; natural antibodies; non obese diabetic NOD ; T cell mediated autoimmunity; allophenic chimeras;

   Sammanfattning : .... LÄS MER

3. 2. Immune responses to the Ro and La autoantigens

   Författare :Pia Tengnér; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Sjögren s syndrome; systemic lupus erythematosus; Ro SS-A; La SS-B;

   Sammanfattning : Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are rheumatic diseases characterized by autoantibody production directed to the Ro/SS-A and La/SS-B autoantigens. The Ro/SS-A is a complex of one of four small RNAs denoted hY RNAs, and three proteins; Ro 60kD, Ro 52kD and La. LÄS MER

4. 3. RNA-protein complexes as autoantigens : cell and molecular biology of Ro/SSA and disease associations of anti-Ro/SSA antibodies

   Författare :Nader Pourmand; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ro SSA; Ro 52kD; Ro 60kD; p40phox; Ig classes; systemic lupus erythematosus; Sjögren s syndrome; autoantibodies; immunoblotting;

   Sammanfattning : Autoantibodies to the Ro/SSA and La/SSB antigens are present in sera from patients with Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE). The Ro/SSA autoantigen consists of a 52kD and a 60kD protein, complexed with one of four small RNAs. The La protein can also associate with the complex. LÄS MER

5. 4. Autoantibodies in congenital heart block

   Författare :Robert Klauninger; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Neonatal lupus erythematosus (NLE) affects neonates of Ro/SSA and La/SSB positive women. NLE is associated with several clinical manifestations including skin rash, cytopenia and congenital heart block (CHB). CHB is the most severe manifestation which can develop into a lethal atrioventricular (AV) block. LÄS MER

7. 5. Protein interactions involved in viral replication characterized by T7 phage display

   Författare :Hamid Houshmand; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; protein-protein interaktion; fagdisplayteknik; HCV; polyomavirus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

   Sammanfattning : Protein interactions are essential for many cellular processes. By utilizing protein-protein interactions, viruses can infect their host cells and replicate. Phage display can be used for identification and characterization of protein-protein interactions. LÄS MER