Sökning: "investigative approach"

Visar resultat 6 - 10 av 26 avhandlingar innehållade orden investigative approach.

  1. 6. A modular mRNA approach to study and treat phospholamban mediated cardiomyopathies

    Författare :Eduarde Rohner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the heart, phospholamban (PLN) is a key regulator of calcium cycling through its inhibitory effect on the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump. For more than two decades, modulating calcium channels has been a strong focus of prospective cardiac therapeutics with a recent emphasis on targeting PLN itself, partially due to the progressive uncovering of several cardiomyopathic PLN human mutations. LÄS MER

  2. 7. Tyre-road Interaction: a holistic approach to noise and rolling resistance

    Författare :Tiago Vieira; Sigurdur Erlingsson; Ulf Sandberg; Anders Genell; Hans Jonasson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; pavement; surface; texture; noise; rolling resistance; tyre; Vägbeläggning; vägyta; textur; buller; rullmotstånd; däck; Byggvetenskap; Civil and Architectural Engineering;

    Sammanfattning : Energy dissipation, fuel consumption, real-estate property prices and health issues are some of the aspects related to the tyre/pavement interaction and its functional properties of rolling resistance and noise. The first two aspects are affected by the tyre/road interaction as energy is dissipated mostly by hysteretic losses as the tyre is subjected to dynamic deformations when contacting the pavement surface. LÄS MER

  3. 8. Tyre/road interaction : A holistic approach to the functional requirements of road surfaces regarding noise and rolling resistance

    Författare :Tiago Vieira; Sigurdur Erlingsson; Ulf Sandberg; Tony Parry; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Road; surface; noise; rolling resistance; tyre; mitigation; Vägbeläggning; vägyta; textur; buller; rullmotstånd; däck; Building Materials; Byggnadsmaterial;

    Sammanfattning : Increased fuel consumption, increased greenhouse gas emission, diminishing real-estate prices and increased health issues are some of  the negative effects on the climate, on the environment and on the society from tyre/road rolling resistance and noise. The first two aspects are affected by energy dissipation in the tyre/pavement contact and are related to rolling resistance. LÄS MER

  4. 9. Learning Physics Through Communication During Laboratory Work : An empirical study at upper secondary school

    Författare :Jan Andersson; Margareta Enghag; Carl Angell; Karlstads universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Physics education; Laboratory Work; Inquiry; Communication; Discourse Analysis; Physics; Fysik;

    Sammanfattning : Laboratory work as a teaching and learning method is given prominence in the Swedish physics curriculum for upper secondary school. It is emphasised that students should be given opportunities to develop the ability to search for answers to questions, plan, conduct, interpret and present results. LÄS MER

  5. 10. Copyright in the Age of Access to Legal Digital Content : A study of EU copyright law in the context of consumptive use of protected content

    Författare :Kacper F. Szkalej; Sanna Wolk; Maria Bergström; Johan Axhamn; Marcus Norrgård; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; copyright; intellectual property; EU law; law and technology; DRM; consumer protection law; Civil Law; Civilrätt; Europarätt; European Integration Law;

    Sammanfattning : In a world where copyright is being infringed in a plethora of ways, consumers find it difficult to access legal digital content. Therefore, this thesis investigates how copyright law governs access to legal content in the digital environment in respect of so-called consumptive use. LÄS MER