Sökning: "hypothyroidism"

Visar resultat 6 - 10 av 46 avhandlingar innehållade ordet hypothyroidism.

  1. 6. Evaluation of the Swedish screening programme for congenital hypothyroidism : a clinical and experimental study

    Författare :Adam Ilicki; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 7. Molecular regulation of thyroid development. New mechanisms of normal and defective morphogenesis

    Författare :Henrik Fagman; Göteborgs universitet; []
    Nyckelord :thyroid; congenital hypothyroidism; thyroid dysgenesis; cadherins; pharyngeal arch arteries; Shh; Tbx1;

    Sammanfattning : Congenital hypothyroidism (CH) is untreated a major cause of mental retardation. The majority of cases are due to malformations of the gland (dysgenesis). Little is known of molecular mechanisms regulating thyroid morphogenesis. LÄS MER

  4. 8. Transcriptional regulation of thyroid development possible interplay of endoderm- and mesoderm-derived morphogenetic signals

    Författare :Jessica Westerlund; Göteborgs universitet; []
    Nyckelord :thyroid; congenital hypothyroidism; dysgenesis; Tbx1; Shh; Isl1; Foxa2; C-cells;

    Sammanfattning : Congenital hypothyroidism (CH) affects 1 in 3000 children and is the major cause of treatable mental retardation. Most cases are due to malformations of the gland, collectively named thyroid dysgenesis. The disease results from defective thyroid organogenesis during embryonic life. LÄS MER

  5. 9. Aspects of diagnosis and treatment of hypopituitarism in adult life

    Författare :Helena Filipsson; Göteborgs universitet; []
    Nyckelord :hypopituitarism; pituitary; diagnosis; treatment; GHD; central hypothyroidism; genetic; idiopathic; ACTH insufficiency; discontinuation;

    Sammanfattning : Management of adult patients with hypopituitarism can improve with better char¬ac¬terisation of idiopathic pituitary insufficiency (IPI) and clearer diagnosis of central hy¬pothy¬roidism (CH). Moreover, optimised treatment strategies for glucocorticoid (GC) re¬placement therapy and of long-term growth hormone (GH) in GH deficiency (GHD) are needed. LÄS MER

  7. 10. Molecular investigations on chromosome 21 in relation to Down syndrome and familial congenital hypothyroidism

    Författare :Bodil Edman Ahlbom; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Genetik; Clinical genetics; Klinisk genetik; Clinical Genetics; klinisk genetik;

    Sammanfattning : Chromosomal abnormalities as well as mutations in single genes are genetic changes that can cause syndromes or inherited diseases. Down syndrome (DS), usually a consequence of trisomy 21, is a gene dosage disorder caused by an extra copy of genes on chromosome 21, but the mechanisms whereby specific genes contribute to the clinical features of DS are not known. LÄS MER