Sökning: "hypopituitarism"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet hypopituitarism.

  1. 1. Aspects of diagnosis and treatment of hypopituitarism in adult life

    Författare :Helena Filipsson; Göteborgs universitet; []
    Nyckelord :hypopituitarism; pituitary; diagnosis; treatment; GHD; central hypothyroidism; genetic; idiopathic; ACTH insufficiency; discontinuation;

    Sammanfattning : Management of adult patients with hypopituitarism can improve with better char¬ac¬terisation of idiopathic pituitary insufficiency (IPI) and clearer diagnosis of central hy¬pothy¬roidism (CH). Moreover, optimised treatment strategies for glucocorticoid (GC) re¬placement therapy and of long-term growth hormone (GH) in GH deficiency (GHD) are needed. LÄS MER

  3. 2. Non-functioning pituitary adenomas and hypopituitarism - studies on morbidity and mortality

    Författare :Casper Hammarstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-functioning pituitary adenomas; Hypopituitarism; Glucocorticoid replacement; Growth hormone replacement; Morbidity; Mortality; Cancer; LDL-cholesterol;

    Sammanfattning : Background and aims: Hypopituitarism is most commonly caused by benign pituitary tumors, often resulting in insidious symptoms that develop over a long time. Due to either a mass effect exerted by the tumor, or due to the surgical treatment, hormonal deficiencies may arise, requiring hormone replacement. LÄS MER

  4. 3. Cardiovascular mortality and morbidity in hypopituitary patients and metabolic effects of growth hormone treatment

    Författare :Birgitta Bulow; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose metabolism; growth hormone replacement; growth hormone deficiency; long-term survival; craniopharyngioma; cardiovascular risk factors; Hypopituitarism; cardiovascular mortality; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Premature atherosclerosis, cardiovascular risk factors and increased cardiovascular mortality have been shown in patients with hypopituitarism on conventional hormone treatment, but without growth hormone (GH) replacement. The aims of paper I-III were to investigate separately the risks for cerebrovascular and cardiac mortality as well as the incidence of cardiovascular disease in patients with hypopituitarism and to assess the long-term prognosis for patients with craniopharyngioma. LÄS MER

  5. 4. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

    Författare :Edna J L Barbosa; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone deficiency; hypopituitarism; growth hormone replacement therapy; prediction models; candidate gene approach; polymorphisms; body composition; growth hormone receptor; lipid metabolism; extracellular water; pharmacogenomics;

    Sammanfattning : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. LÄS MER

  7. 5. Pituitary autoantibodies in endocrine disorders

    Författare :Sophie Bensing; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Lymphocytic hypophysitis; hypopituitarism; empty sella syndrome; APS 1; autoantibodies; autoantigen; Secretogranin II; TDRD6.;

    Sammanfattning : Autoimmune endocrine disorders are characterised by the development of autoantibodies to specific autoantigens in the target organs. Lymphocytic hypophysitis (LyH) is a disease characterised by inflammation of the pituitary gland, often resulting in hypopituitarism. The aetiology of LyH is considered to be autoimmune. LÄS MER