Sökning: "growth hormone GH"

Visar resultat 21 - 25 av 125 avhandlingar innehållade orden growth hormone GH.

  1. 21. The effects of growth hormone on opioid-induced toxicity in vitro

    Författare :Erik Nylander; Mathias Hallberg; Alexis Bailey; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; opioids; methadone; morphine; ketobemidone; fentanyl; oxycodone; hydromorphone; insulin-like growth factor; cell viability; NG108-15; SH-SY5Y; hippocampus; cortex; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : There is an ongoing opioid crisis in the United States that is portrayed by a large number of opioid-related deaths. Many of these cases involve commonly used prescription opioids, such as morphine, oxycodone, fentanyl, and methadone. This is concerning and highlights the problems associated with long-term opioid treatment. LÄS MER

  3. 22. Negative regulation of growth hormone (GH) signaling

    Författare :Elizabeth Rico Bautista; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Growth Hormone (GH) regulates postnatal longitudinal growth. It also has several other functions. It decreases cholesterol and lipoproteins levels, reduces fat tissue and increases lean body mass. GH actions are mediated by the JAK2/STAT5 signaling pathway. LÄS MER

  4. 23. Health-Related Quality of Life and Growth Hormone Treatment : Long-term follow-up studies of women with Turner Syndrome and women with osteoporosis

    Författare :Emily Krantz; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Health-related Quality of Life; Growth hormone; Turner syndrome; Postmenopausal osteoporosis;

    Sammanfattning : Introduction Growth Hormone (GH) is used to increase height in Turner Syndrome (TS), the most common sex-chromosome aberration in women. GH is also beneficial for bone mass. However, little is known about how GH treatment affects Health-Related Quality of Life (HRQoL). LÄS MER

  5. 24. Cardiovascular mortality and morbidity in hypopituitary patients and metabolic effects of growth hormone treatment

    Författare :Birgitta Bulow; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose metabolism; growth hormone replacement; growth hormone deficiency; long-term survival; craniopharyngioma; cardiovascular risk factors; Hypopituitarism; cardiovascular mortality; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Premature atherosclerosis, cardiovascular risk factors and increased cardiovascular mortality have been shown in patients with hypopituitarism on conventional hormone treatment, but without growth hormone (GH) replacement. The aims of paper I-III were to investigate separately the risks for cerebrovascular and cardiac mortality as well as the incidence of cardiovascular disease in patients with hypopituitarism and to assess the long-term prognosis for patients with craniopharyngioma. LÄS MER

  7. 25. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat

    Författare :Kristina Wallenius; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; insulin-like growth factor I IGF-I ; interleukin-6 IL-6 ; growth hormone GH ; GH releasing factor GHRF ; GH secretagogue GHS ; receptor; leptin; insulin; glucose; intracerebroventricular ICV ; dual-energy X-ray absorptiometry DXA ; indirect calorimetry.;

    Sammanfattning : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. LÄS MER