Sökning: "glycogen synthesis"
Visar resultat 1 - 5 av 25 avhandlingar innehållade orden glycogen synthesis.
1. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia
Sammanfattning : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. LÄS MER
2. Two new disorders of glycogen metabolism
Sammanfattning : Glycogen is a polymer of glucose and serves as a source of rapidly available energy. Glycogen synthesis is initiated by autoglucosylation of glycogenin. Two glycogenin genes, GYG1 and GYG2, encode the two isoforms glycogenin-1 and -2, respectively. LÄS MER
3. Studies on exercise and glycogen re-synthesis in skeletal muscles of pigs with the PRKAG3 mutation
Sammanfattning : AMP-activated protein kinase (AMPK) plays an important role in the regulation of glucose and lipid metabolism in skeletal muscle. Many pigs of Hampshire origin have a naturally occurring mutation situated in the PRKAG3 gene which encodes a muscle-specific isoform of the AMPK γ3-subunit. LÄS MER
4. Liver regeneration : With reference to malnutrition and growth factors
Sammanfattning : The liver has a unique capacity to regenerate after damage, irrespective of cause. The regulatory mechanisms of this regeneration are not fully known. Liver regeneration· is associated with rapid growth and thereby increased demands for energy and synthesis of new compounds. LÄS MER
5. Glucose metabolism in patients with exocrine pancreatic adenocarcinoma
Sammanfattning : Carc.inoma of the exocrine pancreas is the fifth leading cause of cancer death in the Western world and the survival rate is one of the lowest for cancers of any site. Pancreatic cancer is characterized by pronounced, early cachexia and frequent metabolic complications. LÄS MER