Sökning: "fetal liver cells"

Visar resultat 6 - 10 av 48 avhandlingar innehållade orden fetal liver cells.

  1. 6. Molecular regulation of rat histidine decarboxylase

    Författare :Christine Dartsch; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physiology; omeprazole; antiserum; fetal rat liver; COS-7 cells; purification; bacterial expression; protein turnover; ECL cells; gastric mucosa; gastrin; histdine decarboxylase; histamine; Fysiologi; Proteins; enzymology; Proteiner; enzymologi;

    Sammanfattning : Histamine is involved in a variety of physiological processes like gastric acid secretion, inflammation and neurotransmission. The production of histamine is catalysed by the enzyme histidine decarboxylase (HDC), which is a strongly regulated enzyme. LÄS MER

  3. 7. Cellular pathways and molecular regulation of hematopoietic stem cells

    Författare :Kristina Anderson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-catenin.; lineage commitment; hematopoietic stem cells; lineage priming; Wnt signaling pathway; biphenotypic cells; PAX5;

    Sammanfattning : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. LÄS MER

  4. 8. Experimental studies of human fetal liver cells : in regard to in utero hematopoietic stem cell transplantation

    Författare :Bim Lindton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :In utero transplantation; fetal liver cells; mixed lymphocyte culture; CD3; CD56; HLA class II; parvovirus B 19 capsids; corticosteroids; cytotoxic drugs; colony formation.;

    Sammanfattning : Successful in utero hematopoietic stem cell transplantation represents a potential step forward in the management of patients with severe inherited hematological, metabolic and immunological disorders. Animal data from a number of species have demonstrated evidence of engraftment, but to date the only effective in utero transplantations (IUTx) in humans have been performed in fetuses with severe immunodeficiencies, suggesting that the fetal immune system play a vital role in the success or failure of in utero transplantation. LÄS MER

  5. 9. Experimental models with specific approaches to augment human fetal liver cell engraftment

    Författare :Pradeep B Patil; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; Cell therapy; Animal models;

    Sammanfattning : Experimental models with specific approaches to augment human fetal liver cell engraftment Pradeep Patil Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg Background: Liver disease is a common cause of morbidity and mortality worldwide. Orthotopic liver transplantation has so far been the only available therapy for patients with end-stage liver failure. LÄS MER

  7. 10. Cellular replacement therapy for liver disease

    Författare :Mohammed Abdel Salam M Saliem; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Liver disease is a major health problem worldwide. The liver performs a wide range of functions, which the human body cannot survive without. The human liver is continuously challenged with infectious organisms, alcohol and chemicals, congenital defects, autoimmunity and malignancy etc. LÄS MER