Sökning: "protein turnover"

Visar resultat 1 - 5 av 188 avhandlingar innehållade orden protein turnover.

1. 1. The effect of protein intake and physical exercise on energy turnover and substrate utilisation at energy balance in man

   Författare :Anders H. Forslund; Uppsala universitet; []
   Nyckelord :Medical sciences; Body composition; carbohydrate; energy turnover; fat; protein; stable isotopes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Nutrition; näringslära;

   Sammanfattning : The principal goal of the thesis has been to evaluate the effect of protein intake and physical exercise on energy turnover and substrate utilisation. Body composition assessment is of importance as an indicator of the energy balance. Therefore, in the first study the aim was to develop new models to estimate body composition more accurately. LÄS MER

3. 2. Zinc in folding and misfolding of SOD1 : Implications for ALS

   Författare :Lina Leinartaité; Mikael Oliveberg; Bengt-Harald Jonsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein stability; protein misfolding; local unfolding; metal binding; energy landscape; protein disease; amyotrophic lateral sclerosis; Biochemistry; biokemi;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing degeneration of upper and lower motor neurons. Most ALS cases are sporadic; only 6% are associated with mutations in Cu, Zn superoxide dismutase (SOD1). LÄS MER

4. 3. Amino acid and protein turnover in human skeletal muscle

   Författare :Rokhsareh Farrah Vesali; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Critically ill patients are characterised by a severe net protein catabolism. The rate of muscle protein loss is in the magnitude of 10% per week. A consequence of muscle wasting is increased weakness, which is associated with high rates of mortality and morbidity. LÄS MER

5. 4. Interconnectivity of mitochondrial protein biogenesis and homeostasis

   Författare :Carmela Vázquez Calvo; Martin Ott; Jan Riemer; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; proteostasis; protein quality control; chaperones; biokemi; Biochemistry;

   Sammanfattning : To ensure correct protein function, the cells are equipped with a tightly regulated network of chaperones that support protein folding and actively participate in protein quality control (PQC) and turnover. Due to the dual origin of the mitochondrial proteome, the cytosolic and mitochondrial PQC networks coordinate to ensure protein import and assembly in the organelle. LÄS MER

7. 5. Constraint-based modeling of yeast metabolism and protein secretion

   Författare :Feiran Li; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein secretion; metabolism; yeast evolution; genome-scale metabolic model; phenotype diversity;

   Sammanfattning : Yeasts are extensively exploited as cell factories for producing alcoholic beverages, biofuels, bio-pharmaceutical proteins, and other value-added chemicals. To improve the performance of yeast cell factories, it is necessary to understand their metabolism. LÄS MER