Sökning: "Bim Lindton"

Hittade 1 avhandling innehållade orden Bim Lindton.

1. 1. Experimental studies of human fetal liver cells : in regard to in utero hematopoietic stem cell transplantation

   Författare :Bim Lindton; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :In utero transplantation; fetal liver cells; mixed lymphocyte culture; CD3; CD56; HLA class II; parvovirus B 19 capsids; corticosteroids; cytotoxic drugs; colony formation.;

   Sammanfattning : Successful in utero hematopoietic stem cell transplantation represents a potential step forward in the management of patients with severe inherited hematological, metabolic and immunological disorders. Animal data from a number of species have demonstrated evidence of engraftment, but to date the only effective in utero transplantations (IUTx) in humans have been performed in fetuses with severe immunodeficiencies, suggesting that the fetal immune system play a vital role in the success or failure of in utero transplantation. LÄS MER