Sökning: "exposure in vivo"

Visar resultat 26 - 30 av 430 avhandlingar innehållade orden exposure in vivo.

  1. 26. The Hepatobiliary Transport of Rosuvastatin In Vivo

    Författare :Ebba Bergman; Hans Lennernäs; Ulf Bondesson; Jack Cook; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rosuvastatin; Biliary excretion; Transport inhibition; Pharmacokinetics; Drug-drug interactions; Hepatobiliary transport; Organic anion transporting polypeptide; OATP; Statins; Gemfibrozil; Cyclosporine; Imatinib; Rifampicin; Canalicular transport; Sinusoidal transport; Hepatic uptake; Hepatic extraction; Biopharmacy; Biofarmaci; Biopharmaceutics; biofarmaci;

    Sammanfattning : In vivo studies of hepatobiliary disposition are challenging. The hepatobiliary system is complex, as its physiological localization, complex cellular structure with numerous transporters and enzymes, and the interindividual variability in protein expression and biliary flow will all affect the in vivo disposition of a drug under investigation. LÄS MER

  2. 27. Orchestrating Virtual Reality Exposure Therapy

    Författare :Marius Koller; Cristian M Bogdan; Gerrit Meixner; Anders Lundström; Oana Mitrut; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Virtual Reality Exposure Therapy; Virtual Reality; Human-Computer Interaction; Mental Health; Teknikvetenskapens lärande och kommunikation; Education and Communication in the Technological Sciences;

    Sammanfattning : Systems for Virtual Reality Exposure Therapy (VRET) are shaping the future of therapy of anxiety disorders, especially at a time when we are seeing an increase in virtual meetings in almost every context in life. Exposure therapy is an established therapy method in the treatment of anxiety disorders. LÄS MER

  3. 28. Neurotrophins and nitric oxide in relation to airway responses in experimental asthma in vivo

    Författare :Lydia Bennedich Kahn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma is an inflammatory disease of allergic or non-allergic genesis characterized by intermittent reversible airway obstruction and variable degrees of persistent airway hyperresponsiveness (AHR). Increase in AHR likely arises from augmented airway inflammation, such as associated with a late airway response. LÄS MER

  4. 29. Studies on Pellicle and Early Dental Plaque in Relation to Periodontal Conditions

    Författare :Stefan G Rüdiger; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacterial adherence; in vitro pellicle; in vivo pellicle; periodontitis-associated bacteria; gingival crevicular fluid; plasma proteins; dental biofilm; experimental gingivitis; chronic periodontitis; periodontal pocket; exposed root surfaces;

    Sammanfattning : Background and Hypothesis: Bacterial receptors in dental pellicles may influence colonisation and subsequent plaque formation. Studies on such receptors in the dental pellicles and bacterial adherence have mostly been performed in vitro and focused on proteins of salivary origin. LÄS MER

  5. 30. Dendritic cells and Plasmodium falciparum: studies in vitro and in the human host

    Författare :Pablo Giusti; Marita Troye-Blomberg; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Malaria is one of the world’s most threatening diseases. About half the world’s population is at risk of infection and the infection claims a million lives each year. A vast majority of the deaths occur in children below the age of 5 in sub-Saharan Africa. LÄS MER