Sökning: "Cardiac tissue"

Visar resultat 1 - 5 av 229 avhandlingar innehållade orden Cardiac tissue.

  1. 1. Cardiac hypertrophy : transcription patterns, hypertrophic progression and extracellular signalling

    Författare :Nina Gennebäck; Stellan Mörner; Anders Waldenström; Urban Hellman; Ali J Marian; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac hypertrophy; HCM; gene expression; OPLS-DA; multivariate dataanalysis; cardiomyocytes; exosomes; microvesicles; Medicine; medicin;

    Sammanfattning : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. LÄS MER

  3. 2. Evaluation of Myocardial Function in Chronic Kidney Disease : A Colour Tissue Velocity Imaging Study

    Författare :Shirley Hayashi; Lars-Åke Brodin; Svend Aakhus; KTH; []
    Nyckelord :Cardiac; Kidney; Tissue; Velocity; MEDICINE; MEDICIN;

    Sammanfattning : In patients with chronic kidney disease (CKD), overhydration, uremic toxins and left ventricular (LV) dyssynchrony are factors that may lead to LV dysfunction and conduction abnormalities and thus contribute to the high cardiac mortality. Colour tissue velocity imaging (TVI) allows a detailed quantitative analysis of cardiac function in CKD patients, opening new possibilities to evaluate longitudinal myocardial motion, rapid isovolumetric events, LV filling pressure and LV synchronicity. LÄS MER

  4. 3. S100B and Cardiac Surgery

    Författare :Henrik Bjursten; Thoraxkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100-B; S100B; S100beta; brain damage; cardiac surgery; CABG; renal function; autotransfusion; Cardiovascular system; serum marker; Kardiovaskulära systemet;

    Sammanfattning : The brain-derived protein S100B is a 21 Kda dimerand have been used as a serum marker for brain damage of different etiology. The feasability of protein S100B as serum marker for brain damage after cardiac surgery was studied in this thesis. One unexpected finding was made, which changed the basis for interpration of S100B levels. LÄS MER

  5. 4. Physiology of Adventure Racing : with emphasis on circulatory response and cardiac fatigue

    Författare :C. Mikael Mattsson; Björn Ekblom; Keith P George; Gymnastik- och idrottshögskolan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; cardiovascular drift; cardiac fatigue; adventure race; cardiac biomarkers; cardoac function; exercise echocardiography; Physiology; Fysiologi; Cardiology; Kardiologi; Sports; Idrott; Medicin Teknik; Medicine Technology;

    Sammanfattning : The overall aims of this thesis were to elucidate the circulatory responses to ultra-endurance exercise (Adventure Racing), and furthermore, to contribute to the clarification of the so called “exercise-induced cardiac fatigue” in relation to said exercise. An Adventure race (AR) varies in duration from six hours to over six days, in which the participants have to navigate through a number of check-points over a pre-set course, using a combination of three or more endurance/outdoor sports, e. LÄS MER

  7. 5. Quantitative cardiac 15O-water PET : Assessment of left-ventricular function, remodeling, and impact of patient motion

    Författare :Jonny Nordström; Mark Lubberink; Jens Sörensen; Hendrik J Harms; Stephan Nekolla; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; positron emission tomography PET ; 15O-water; myocardial blood flow; cardiac remodeling; patient motion;

    Sammanfattning : International guidelines advocate the use of noninvasive cardiac imaging as the initial diagnostic test for coronary artery disease, the global leading cause of death according to the world health organization. Within the wide spectrum of cardiac imaging, 15O-water PET is the gold standard for noninvasive quantification of myocardial blood flow (MBF). LÄS MER