Sökning: "endogenous factors"

Visar resultat 11 - 15 av 315 avhandlingar innehållade orden endogenous factors.

  1. 11. Endogenous Opioids and Voluntary Ethanol Drinking : Consequences of Postnatal Environmental Influences in Rats

    Författare :Lisa Gustafsson; Ingrid Nylander; Erika Roman; Ryszard Przewlocki; Uppsala universitet; []
    Nyckelord :Pharmaceutical pharmacology; Maternal separation; Maternal deprivation; Handling; Isolation; Alcohol; Two-bottle model; Four-bottle model; MEAP; Dynorphin B; Nociceptin orphanin FQ; Radioimmunoassay; Farmaceutisk farmakologi;

    Sammanfattning : Genetic and environmental factors interact to determine the individual vulnerability to develop ethanol dependence. The neurobiological mechanisms underlying these processes are not fully understood. Endogenous opioid peptides have been suggested to contribute. LÄS MER

  3. 12. Identification and origin of potential background carcinogens : endogenous isoprene and oxiranes, dietary acrylamide

    Författare :Eden Tareke; Rafter Joseph; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; Miljökemi; Environmental Chemistry; miljökemi;

    Sammanfattning : The primary aims of this thesis are to discover carcinogens in the general population by identification of products of reaction with hemoglobin (Hb adducts) in blood from humans without known exposure, and tracing the origin of the adducts. Chemicals and/or their metabolites forming Hb adducts mostly also react with DNA and may thus cause mutations, a key event in carcinogenesis. LÄS MER

  4. 13. Endogenous and exogenous hormonal factors in female cancers : studies of risk and prognosis

    Författare :Chantal Claudine Orgéas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Extensive evidence points to hormonal influences which play a critical role in the development and progression of breast, ovarian and endometrial or uterine cancers. These cancers share many common hormonal features, which are crucial in the etiology and subsequent development of these cancers. LÄS MER

  5. 14. Reproductive and lifestyle risk factors for sarcoidosis

    Författare :Marina Dehara; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Sarcoidosis is a systemic inflammatory condition with an unknown origin, characterized by the formation of granulomatous lesions primarily in the lungs and lymphatic system. Despite over a century since it was first described, our understanding of its etiology remains limited. LÄS MER

  7. 15. Liver regeneration : With reference to malnutrition and growth factors

    Författare :Stefan Skullman; Linköpings universitet; []
    Nyckelord :cholecystokinin; energy substrates; epidermal growth factor; insulin-like growth factor I; liver composition; liver regeneration; malnutrition; pancreaticobiliary diversion; protein synthesis; rat; transfonning growth factor alpha; MEDICINE; MEDICIN;

    Sammanfattning : The liver has a unique capacity to regenerate after damage, irrespective of cause. The regulatory mechanisms of this regeneration are not fully known. Liver regeneration· is associated with rapid growth and thereby increased demands for energy and synthesis of new compounds. LÄS MER