Sökning: "copy number analysis"

Visar resultat 31 - 35 av 157 avhandlingar innehållade orden copy number analysis.

  1. 31. Genetic characterization of malignant melanoma and breast cancer

    Författare :Göran B Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; microarray; inherited breast cancer; Melanoma; linkage analysis; cancer; Cytologi; cancerology; onkologi;

    Sammanfattning : Malignant melanoma and breast cancer are common malignant diseases characterized by considerable heterogeneity with respect to genetics, histopathology, biology and clinical course. In breast cancer, two major susceptibility genes have been identified, BRCA1 and BRCA2, which account for a significant proportion of high-risk breast cancer families. LÄS MER

  3. 32. Essays on Efficiency, Productivity, and Impact of Policy

    Författare :Pontus Mattsson; Jonas Månsson; Lars Behrenz; Almas Heshmati; Linnéuniversitetet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; conditional difference-in-differences cDiD ; courts; data envelopment analysis DEA ; Malmquist index; horizontal mergers; impacts of policy; stochastic frontier analysis SFA ; subsidized employment; total factor productivity TFP ; Törnqvist TFP index; Economics; Nationalekonomi;

    Sammanfattning : This thesis consists of five self-contained empirical essays centering on total factor productivity (TFP), efficiency, and impacts of policy.Essay I: “TFP Change and Its Components for Swedish Manufacturing Firms During the 2008-2009 Financial Crisis” (co-authored with Jonas Månsson and William H. Greene). LÄS MER

  4. 33. Mitochondrial Genome Analysis Using Next Generation Sequencing for Forensic Applications

    Författare :Kimberly Sturk-Andreaggi; Marie Allen; Antti Sajantila; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial DNA; next generation sequencing; massively parallel sequencing; forensic genetics; nuclear mitochondrial DNA segment NUMT ; length heteroplasmy; haplogroup; quality control; population data; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Mitochondrial DNA (mtDNA) analysis plays a specialized role in forensic applications, overcoming certain limitations of autosomal DNA markers. The high copy number and uniparental inheritance pattern of mtDNA are advantageous in cases involving shed hairs and aged skeletal elements, especially decades-old missing persons cases. LÄS MER

  5. 34. Spatial transcriptome and epigenome analysis with focus on prostate cancer

    Författare :Maja Marklund; Joakim Lundeberg; Patrik Ståhl; Marc Friedländer; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial; Spatial Transcriptomics; Spatial ATAC; epigenomics; Biotechnology; Bioteknologi;

    Sammanfattning : Each cancer is unique, and therefore the use of general treatments are often suboptimal. If we can understand the mechanisms of cancer development, we might be able to develop effective treatments tailored to each patient. Our bodies are complex three-dimensional structures and how things are organized correlate with proper functioning. LÄS MER

  7. 35. Automating Reuse in Web Application Development

    Författare :Josip Maras; Ivica Crnković; Jan Carlson; Maja Štula; Martin Robillard; Mälardalens högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; web applications; reuse; program analysis; Computer Science; datavetenskap;

    Sammanfattning : Web applications are one of the fastest growing types of software systems today. Structurally, they are composed out of two parts: the server-side, used for data-access and business logic, and the client-side used as a user-interface. LÄS MER