Sökning: "inherited breast cancer"
Visar resultat 1 - 5 av 23 avhandlingar innehållade orden inherited breast cancer.
1. Genetic characterization of malignant melanoma and breast cancer
Sammanfattning : Malignant melanoma and breast cancer are common malignant diseases characterized by considerable heterogeneity with respect to genetics, histopathology, biology and clinical course. In breast cancer, two major susceptibility genes have been identified, BRCA1 and BRCA2, which account for a significant proportion of high-risk breast cancer families. LÄS MER
2. On the genetics of hereditary breast/ovarian cancer. BRCA1, BRCA2 and beyond
Sammanfattning : Breast cancer is the most common malignancy in women. Most of the breast cancers are sporadic with no apparent inheritance factor but about 5-10% is believed to be caused by an inherited predisposition. Aims: This thesis aimed at defining the BRCA1/2 mutation spectrum of the west Swedish population and specifically to characterize the BRCA1c. LÄS MER
3. Insights into breast cancer: New familial patterns and identification of a potential predictive marker
Sammanfattning : The last proportion of heredity in breast cancer has proven to be somewhat elusive despite massive attempts to identify the associated factors. Approximately 50 percent of breast cancer caused by familial factors is currently explained. LÄS MER
4. Molecular Epidemiology of Breast Cancer
Sammanfattning : Hereditary breast cancer constitutes a considerable fraction of the total number of breast cancer cases occurring each year. Up until recently very few breast cancer predisposing genes were known, but many new common polymorphisms contributing to increased cancer susceptibility are continuously being identified. LÄS MER
5. Exploring vitamin D and steroid hormone receptors – from healthy elderly to prostate cancer cells
Sammanfattning : The genetic background together with environmental factors and lifestyle are key contributors to the health of an individual. Genetic background is inherited and irreversible unless mutations occur. However, lifestyle habits (i.e. LÄS MER