Sökning: "clonal heterogeneity"

Visar resultat 11 - 15 av 34 avhandlingar innehållade orden clonal heterogeneity.

  1. 11. Molecular epidemiology of streptococcus agalactiae : mobile elements as genetic markers

    Författare :Shi-Lu Luan; Mari Norgren; Barbara Spellerberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus agalactiae; group II intron GBSi1 ; multilocus sequence typing; capsular serotype; population structure; Clinical bacteriology; Klinisk bakteriologi;

    Sammanfattning : Streptococcus agalactiae, also designated group B streptococcus (GBS), is a Gram-positive coccus, and it is an important pathogen that causes invasive disease in neonates, pregnant adults, and non-pregnant adults with predisposing conditions. The group II intron GBSi1 is one of the major mobile genetic elements identified in S. agalactiae. LÄS MER

  3. 12. A forest dark : an evolutionary history of Norway spruce

    Författare :Alexis R. Sullivan; Xiao-Ru Wang; Nathaniel Street; María Rosario García-Gil; Bengt Oxelman; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phylogenetics; genome assembly; recombination; Picea; hybridization; mitogenome; Norway spruce; phylogeography; phylogenetic networks; plastome;

    Sammanfattning : Embedded within the relationships among species is a dense forest of gene trees, each with a potentially unique and discordant history. Such widespread genealogical heterogeneity is expected, but embracing this hierarchy of discordance while reconstructing the histories of populations and species remains a major challenge. LÄS MER

  4. 13. Genotypic and phenotypic characterization of Porphyromonas gingivalis in relation to virulence

    Författare :Takashi Yoshino; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Porphyromonas gingivalis; Phenotype; Genotype; Virulence; Periodontitis;

    Sammanfattning : The present thesis was designed to increase the knowledge on the role of pathogenic potential of Porphyromonas gingivalis as a putative periodontal pathogen. P. LÄS MER

  5. 14. Molecular and phenotypic characterization of diarrhoeagenic Escherichia coli from Nicaraguan children

    Författare :Bayardo Samuel Vilchez Rugama; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diarrhoeal diseases continue to be a foremost public health problem worldwide, with over 1.5 million deaths occurring each year, mostly in children in developing countries. In Nicaragua, the mortality due to diarrhoea in children less than 5 years of age is 11 per 10,000 inhabitants. LÄS MER

  7. 15. Phasing single DNA molecules with barcode linked sequencing

    Författare :David Redin; Afshin Ahmadian; Ulf Gyllensten; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Single molecule sequencing; DNA barcoding; whole genome haplotyping; linked-read sequencing; phasing; de novo genome assembly.; Biotechnology; Bioteknologi;

    Sammanfattning : Elucidation of our genetic constituents has in the past decade predominately taken the form of short-read DNA sequencing. Revolutionary technology developments have enabled vast amounts of biological information to be obtained, but from a medical standpoint it has yet to live up to the promise of associating individual genotypes to phenotypic states of wide-spread clinical relevance. LÄS MER