Sökning: "ciprofloxacin"

Visar resultat 21 - 25 av 64 avhandlingar innehållade ordet ciprofloxacin.

1. 21. Organic Azides : Functional Molecules and Materials

   Författare :Giampiero Proietti; Peter Dinér; Per I. Arvidsson; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; perfluorinated Aromatic Azide; Photoactivatable; fluorophores; aggregation-induced emission; sulfonimidamides; sulfoximes; chiral auxilary; organogel; azides reduction; Ni-B; Kemi; Chemistry;

   Sammanfattning : The work presented in this thesis stems from the chemistry of the azido group, and more specifically from the unique reactivity of perfluorinated aromatic azides and how to use this reactivity to access new types of molecules to enable new applications in asymmetric synthesis and materials.In the first section of this thesis, a photoactivatable fluorescence probe is presented, where the non-luminescent azide was activated via a UV-light-promoted intramolecular N–H insertion reaction forming a fluorescence emitter. LÄS MER

3. 22. Role of antimicrobial peptides in combating shigellosis and in antibiotic-associated diarrhea

   Författare :Protim Sarker; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Antimicrobial peptides (AMPs) constitute front-line components of innate immunity in multicellular organisms. AMPs are able to kill a wide range of pathogens and exhibit additional important functions such as chemotaxis, angiogenesis and wound healing. These peptides are constitutively expressed in immune and/or epithelial cells. LÄS MER

4. 23. Epidemiology of Enterococci with Acquired Resistance to Antibiotics in Sweden : Special emphasis on Ampicillin and Vancomycin

   Författare :Erik Torell; Mats Kallin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Antimicrobial resistance; enterococci; epidemiology in Sweden; intra-hospital spread; shedding; risk-factors; infection; colonization; virulence factors; ARE; VRE; Php; PFGE; esp; gyrA; parC; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

   Sammanfattning : The first hospital outbreak of vancomycin-resistant enterococci (VRE) and carriage rates of VRE and ampicillin-resistant enterococci (ARE) in Sweden were investigated. Clonal relationships and mutations in fluoroquinolone resistance determining regions among ARE collected nation-wide were studied. LÄS MER

5. 24. Studies on the molecular mechanisms of resistance to fluoroquinolones and carbapenems in selected bacterial species

   Författare :Nagwa Mustafa El Amin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The emergence of mutant bacteria with multi-resistant phenotype, no longer responsive to any of the available therapeutic agents is a growing concern. We have investigated the resistance mechanisms to two classes of antibacterials with broad spectrum of activity, carbapenems and fluoroquinolones. LÄS MER

7. 25. Resistance to Fluoroquinolones in Escherichia coli: Prevention, Genetics and Fitness Costs

   Författare :Linda L. Marcusson; Diarmaid Hughes; Karl Drlica; Uppsala universitet; []
   Nyckelord :Biology; Fluoroquinolone; Escherichia coli; Resistance; Gyrase; Topoisomerase IV; MPC; Fitness compensation; Urinary Tract Infection; Biologi;

   Sammanfattning : Antibiotic-resistant bacteria are increasingly a major healthcare problem but very few new classes of antibiotics have been discovered or launched in recent decades. Approaches to dealing with the problem include learning how bacteria evolve to resistance and improving dosing regimens with current antibiotics so as to reduce the selection of resistant bacteria. LÄS MER