Sökning: "cell lineage tracing"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden cell lineage tracing.
1. Cell lineage analysis in humans
Sammanfattning : Delineating a cell’s history, where it came from and what has happened to it, can provide clues as to how tissues and organs are formed and function in the healthy state and in disease. The gold standard for tracing the relationships between cells and their progeny, is performed through prospective labeling with dyes or genetics tags. LÄS MER
2. Lymphatic Vascular Morphogenesis : From Progenitors to Functional Vessels
Sammanfattning : The lymphatic vasculature is an important part of the circulatory system and crucial for normal functioning and maintenance of tissues. Yet, our understanding of the processes underlying lymphatic development and homeostasis are surprisingly limited. LÄS MER
3. Determine the developmental dynamics of primordial follicles in the mouse ovary
Sammanfattning : Ovarian follicles are the basic functional units of the mammalian ovary. Progressive activation of primordial follicles serves as the source of fertilizable ova. LÄS MER
4. The Biology of Hematopoietic Stem Cells: transgenic approaches to Dissect Native and Perturbed Hematopoiesis
Sammanfattning : Hematopoiesis is defined as the ongoing production of blood cells. As most mature blood cells are relatively short-lived and require continuous replacement, hematopoiesis is characterized by an extraordinary turnover rate with production of trillions of new blood cells every day. LÄS MER
5. Microfluidics and AI for single-cell microbiology
Sammanfattning : Most of the biological sciences deal with understanding the relationships between phenotypes and the underlying molecular mechanisms of organisms. This thesis is an engineering, computational, and experimental exercise in expanding the scope and scale of phenotype-genotype mapping techniques in single-cell microbiology using microscopy, microfluidics, and image processing. LÄS MER