Sökning: "cell content"

Visar resultat 1 - 5 av 708 avhandlingar innehållade orden cell content.

  1. 1. Protein tyrosine kinases in insulin producing cells : Expression and putative importance for beta-cell function

    Författare :Charlotte Öberg-Welsh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinase; insulin producing cells; fetal development; VEGF; Src-family; Bsk; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Protein tyrosine kinases are of importance for cell replication and differentiation in manysystems. The mechanisms controlling the replication and differentiation of insulin producingcells are unknown. LÄS MER

  3. 2. Generating Dendritic Cells by Direct Cell Reprogramming. Merging cellular reprogramming with immunology towards the development of novel cancer immunotherapies

    Författare :Fábio Fiúza Rosa; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic Cell; Direct Cell Reprogramming; Single-cell analysis; Immunotherapy;

    Sammanfattning : Cell fate reprogramming towards pluripotency or alternative somatic cell-types has highlighted the plasticity of adult somatic cells, providing new technologies to generate desired cell types for tissue repair or for disease modeling. There is momentum to bring these concepts to immunology by specifying unique immune cellular identities that set in motion immune responses. LÄS MER

  4. 3. New Approaches for Chemical Analysis of Single Cells and Vesicles

    Författare :Johan Dunevall; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrochemistry; Analytical chemistry; Chemistry; Exocytosis; Catecholamines;

    Sammanfattning : Exocytosis is the major cell-to-cell communication process in the nervous system, involving the conversion of an electrical signal (e.g. action potential) to a chemical one. Signaling molecules like neurotransmitters, hormones and/or peptides are stored in vesicles inside the cell. LÄS MER

  5. 4. High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

    Författare :Karl-Johan Leuchowius; Ola Söderberg; Ulf Landegren; Paul Goldsmith; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in situ; proximity ligation; flow cytometry; high content screening; rolling circle amplification; in situ PLA; single-cell; single-molecule; protein interactions; drug screening; post-translational modifications; Molecular medicine; Molekylär medicin; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Fundamental to all biological processes is the interplay between biomolecules such as proteins and nucleic acids. Studies of interactions should therefore be more informative than mere detection of expressed proteins. Preferably, such studies should be performed in material that is as biologically and clinically relevant as possible, i.e. LÄS MER

  7. 5. Mechanisms for and Effects of Airway Epithelial Damage in Asthma

    Författare :Anne-Jacqueline Relova; Eythor Björnsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; asthma; airways; cytokines; epithelium; tight junctions; mast cells; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : The airway epithelium plays a crucial role in protecting the underlying connective tissue (CT) from noxious agents. Damage and shedding of the epithelium are observed in the airways of asthma, cystic fibrosis and rhinitis patients. LÄS MER