Sökning: "carbohydrate ester"

Visar resultat 11 - 15 av 16 avhandlingar innehållade orden carbohydrate ester.

  1. 11. Design and synthesis of glycose-derivatives and related molecules for cell membrane mimetics

    Författare :Jing Shi; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : A series of glucopyranose (α-D-glucose, β-D-glucose, D-gluconic acid and 6-amino-6-deoxy-D-glocuse) terminated alkanethiol acetals have been successfully synthesized. α and β-D-glucose were configured in controlled ways coupling with alkanethiol, in which bromosugar and trichloroacetirnidates were selected as activated glycosyl donors using different promoters tetraalkylammonium bromide (Et4NBr) and trimethylsilanetriflate (TMSOTf) respectively. LÄS MER

  3. 12. Hormone-Sensitive Lipase, new roles for an old enzyme

    Författare :Ola Hansson; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; Vitamin A; Inflammation; Medicine human and vertebrates ; Medicin människa och djur ; Metabolism; Hormone-Sensitive Lipase; Proteomics; Obesity; White adipose tissue; Skeletal muscle;

    Sammanfattning : Hormone-sensitive lipase (HSL) has a wide tissue distribution with the highest expression found in white adipose tissue (WAT). HSL also has a unique ability to hydrolyze a large panel of substrates including acylglycerols, cholesteryl esters and retinyl esters. HSL is potentially a new drug target for the treatment of obesity and type II diabetes. LÄS MER

  4. 13. Role of Fatty Acid Composition in Non-Alcoholic Fatty Liver Disease: a Dietary Perspective : Results from Interventional and Observational Studies

    Författare :Michael Fridén; Ulf Risérus; Fredrik Rosqvist; Helen Lindqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty acids; Diet; Biomarkers; NAFLD; Liver fat; Fibrosis; Cirrhosis; HCC; Nutrition; Nutrition;

    Sammanfattning : The overall aim of this doctoral thesis was to investigate the role of circulating, liver and dietary fatty acids in non-alcoholic fatty liver disease (NAFLD). For circulating and liver fatty acids, special emphasis was given to fatty acids reflecting diet. LÄS MER

  5. 14. Biomolecular interactions at model interfaces : a self-assembled monolayer approach

    Författare :Sofia Svedhem; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The overall aim of this thesis has been to explore the use of self-assembled monolayers (SAMs) in model studies of biomolecular binding at interfaces. Molecular details of interfaces are difficult to address experimentally, and in spite of the fact that interactions in the living system commonly occur at interfaces, e.g. LÄS MER

  7. 15. Detailed structural studies towards the understanding of lipopolysaccharide glycan expression in non-typeable Haemophilus influenzae

    Författare :Susanna Lundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Haemophilus influenzae (Hi) is a host-adapted Gram-negative bacterium that regularly colonizes the respiratory tract of humans. Hi is an important cause of disease worldwide and exists in encapsulated and unencapsulated (non-typeable, NT) forms. LÄS MER