Sökning: "NAFLD"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet NAFLD.

  1. 1. Liver-related complications and metabolic comorbidities during long-term follow-up of patients with Non-Alcoholic Fatty Liver Disease

    Författare :Kristina Önnerhag; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease CKD ; Epidemiology; Fibrosis; Hepatocellular cancer; Insulin resistance; Liver cirrhosis; Metabolic syndrome; NAFLD; NASH; Non-alcoholic fatty liver disease; non-alcoholic steatohepatitis;

    Sammanfattning : Background: Non-alcoholic fatty liver disease (NAFLD) is highly associated with the metabolic syndrome, and due to increasing prevalence of for example obesity it is now the most common liver disease in the world. A minority progress to advanced fibrosis/cirrhosis, which is associated with increased mortality, but it is not entirely clear which patients who have an increased risk of fibrosis. LÄS MER

  2. 2. Genetic variants for liver fat accumulation and circulating triglyceride levels

    Författare :Ivana Stojkovic; Diabetes - kardiovaskulär sjukdom; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; genetic variations; triglycerides; ALAT; dietary intake; type 2 diabetes; cardiovascular disease;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD), obesity and type 2 diabetes(T2D) are strongly associated and today their prevalence reaches epidemic proportions. NAFLD has a multi-factorial aetiology, both genetic and environmental factors are equally important. LÄS MER

  3. 3. Protein kinase STK25 is a regulator of hepatic lipid partitioning and whole body metabolism

    Författare :Manoj Amrutkar; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :NAFLD; NASH; Liver lipid metabolism; Type 2 diabetes; STK25;

    Sammanfattning : In past decade, type 2 diabetes (T2D) and associated metabolic complications have become a major global threat for human health with epidemic increase in incidence. Currently available treatments for T2D have several limitations and side effects making it difficult safely reach adequate metabolic control. LÄS MER

  4. 4. Susceptibility to chronic liver disease

    Författare :Maria Antonella Burza; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :chronic liver disease; susceptibility; human genetics; NAFLD; ALD; PNPLA3;

    Sammanfattning : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. LÄS MER

  5. 5. Metabolic and endocrine effects of SGLT2 inhibition

    Författare :Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; Uppsala universitet; []
    Nyckelord :SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. LÄS MER