Sökning: "biologically active compounds"

Visar resultat 16 - 20 av 44 avhandlingar innehållade orden biologically active compounds.

  1. 16. Secondary Metabolites from Bolivian Plants- Isolation and Characterization

    Författare :Marcelo Davila; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phytochemistry; Natural Prodcuts;

    Sammanfattning : Nature has been recognized as a rich source of potentially useful chemicals. Throughout the years, phytochemical studies have led to the discovery of an enormous number of natural products, their chemical diversity is unique and many of them possess various biological activities. LÄS MER

  3. 17. Development of New Efficient Iridium-Catalyzed Methods for the Construction of Carbon-Heteroatom Bonds

    Författare :Elis Erbing; Belén Martín-Matute; Keary Engle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Iridium Catalysis; Method development; Halogenation; Isomerization; C-H Activation; organisk kemi; Organic Chemistry;

    Sammanfattning : Today’s society has a large demand for biologically active chemicals that can be used for example as pharmaceuticals and in the agriculture. These are normally constructed by assembling together several smaller chemical molecules. LÄS MER

  4. 18. Amine Transaminases in Multi-Step One-Pot Reactions

    Författare :Mattias Anderson; Per Berglund; Frank Hollmann; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biocatalysis; enzyme; amine transaminase; ω-transaminase; amination; primary amine; chiral amine; chemoenzymatic; green chemistry; synthesis; cascade; Bioteknologi; Biotechnology;

    Sammanfattning : Amine transaminases are enzymes that catalyze the mild and selective formation of primary amines, which are useful building blocks for biologically active compounds and natural products. In order to make the production of these kinds of compounds more efficient from both a practical and an environmental point of view, amine transaminases were incorporated into multi-step one-pot reactions. LÄS MER

  5. 19. Palladium Catalysis in Directed C-H Bond Activation and Cycloisomerisation Reactions

    Författare :Michael Oschmann; Jan-Erling Bäckvall; Oscar Verho; Jose Luis Mascareñas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Palladium II ; Catalysis; C-H Functionalisation; Transamidation; XAS; organisk kemi; Organic Chemistry;

    Sammanfattning : The main focus of this thesis concerns the development of Pd(II)-catalysed synthetic methodologies for the preparation of biologically active compounds.In the first part (paper I-III), unactivated C–H bonds of a cyclobutane derivative are selectively functionalised using a directing group starting from the feedstock compound verbenone (paper I). LÄS MER

  7. 20. Targeting Biological Systems by Organic Synthesis Methods - Cancer Cells and Proteins

    Författare :Cecilia Winander; Lars Baltzer; Stefan Sjöberg; Jörgen Carlsson; Vladimir Tolmachev; Thomas Schrader; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; carborane; doxorubicin; 125I; molecular recognition; four-helix bundle; polypeptide conjugate; affinity; chitinase; acetylcholine esterase; Organisk kemi;

    Sammanfattning : This thesis describes the design and synthesis of molecules with potential roles in biomedicine, with an emphasis on molecular recognition in complex biological environments. The first chapter describes the synthesis and evaluation of compounds for use in nuclide therapy. LÄS MER