Sökning: "amination"
Visar resultat 1 - 5 av 33 avhandlingar innehållade ordet amination.
1. Glycerol derivatives in the hydrogen autotransfer reaction - Development of C-C and C-N bond forming reactions
Sammanfattning : Glycerol (1,2,3-propanetriol) is obtained as a byproduct in the biodiesel industry. In the quest for more sustainable starting materials for organic synthesis, glycerol with its three alcohol functionalities is a promising candidate. LÄS MER
2. Iridium-Catalyzed C−H Activation Methods for Late-Stage Functionalization of Pharmaceuticals
Sammanfattning : C-H activations have over the recent decades risen from a mere curiosity to a viable synthetic strategy. However, challenges in terms of accessible transformations, selectivity and functional group tolerance limit the widespread applicability of this approach. LÄS MER
3. Amine Transaminases in Multi-Step One-Pot Reactions
Sammanfattning : Amine transaminases are enzymes that catalyze the mild and selective formation of primary amines, which are useful building blocks for biologically active compounds and natural products. In order to make the production of these kinds of compounds more efficient from both a practical and an environmental point of view, amine transaminases were incorporated into multi-step one-pot reactions. LÄS MER
4. Valorisation of Renewable Building Blocks via Transition Metal Catalysis – Glycerol- and Amino Acid Derived Compounds in Hydrogen Borrowing and RuAAC Reactions
Sammanfattning : To a large extent, organic building blocks are today obtained from petroleum-based products. From an environmental point of view, biomass-derived compounds are more sustainable alternatives to such oil-derived molecules. The 12 principles of green chemistry describe how chemical processes can be improved in terms of sustainability. LÄS MER
5. Metal Mediated Synthesis. Synthetic and Mechanistic Investigations of Conjugate Addition and Reductive Amination
Sammanfattning : The thesis is divided into two separate parts, one treating conjugate addition and the other reductive aminations. The first part of the thesis is concerned with organocopper promoted conjugate addition to .alfa.,. LÄS MER