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Visar resultat 16 - 20 av 26 avhandlingar som matchar ovanstående sökkriterier.
16. Synthesis of 11C-labelled monosaccharides
Sammanfattning : The synthesis of some 11C-labelled (tl/2=20.3 min) monosaccharides is presented. Terminal labelled alkenes were synthesized and selectively oxidized using asymmetric dihydroxylation (AD) and palladium(II)-promoted oxidation. The labelled polyols obtained after the AD were submitted to enzymatic oxidations. LÄS MER
17. Synthesis of Nitrogen Heterocycles via 1,3-Dipolar Cycloadditions - Method Development and Applications
Sammanfattning : Because of the diverse properties displayed by nitrogen heterocycles, they are one of the most commonly used structural elements in drug discovery. Due to this variation in properties, however, the chemistry and synthetic pathway to each heterocycle is unique. LÄS MER
18. Influence of Admixtures on Crystal Nucleation of Vanillin
Sammanfattning : Admixtures like reactants and byproducts are solublenon-crystallizing compounds that can be present in industrialsolutions and affect crystallization of the main substance.This thesis provides experimental and molecular modellingresults on the influence of admixtures on crystal nucleation ofvanillin (VAN). LÄS MER
19. Quantum Chemical Modelling of Enzymatic and Organometallic Reactions
Sammanfattning : In this thesis, density functional theory (DFT) is employed in the study of two enzymes and two organometallic systems.First, the natural reaction mechanism, as well as the enantioselective formation of α-hydroxyketones catalysed by two thiamine diphosphate (ThDP)- dependent enzymes, namely benzoylformate decarboxylase (BFDC) and 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid (SEPHCHC)- synthase (MenD), are investigated. LÄS MER
20. Synthesis and evaluation of bicyclic 1,3-diols (BODOLs) as ligands for asymmetric catalysis
Sammanfattning : Several ligands based upon 2-substituted bicyclic[2.2.2]octane-2,6-diols (BODOLs) were synthesized and evaluated in two catalytic reactions: I) the Ti(IV)-mediated catecholborane asymmetric reduction of prochiral ketones and II) as catalysts in the asymmetric addition of diethylzinc to aromatic aldehydes. LÄS MER