Sökning: "CuAAC"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet CuAAC.

  1. 1. Photochemical Ligation Techniques for Carbohydrate Biosensors and Protein Interaction Studies

    Författare :Oscar Norberg; Olof Ramström; Stéphane Vincent; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Biosensors; CuAAC; Photochemistry; Thiol-ene yne; Perfluorophenylazide PFPA ; Lectins; Molecular recognition; Quartz crystal microbalance QCM ; Surface plasmon resonance SPR ;

    Sammanfattning : This thesis concerns the development of surface ligation techniques for the preparation of carbohydrate biosensors. Several methodologies were developed based on efficient photochemical insertion reactions which quickly functionalize polymeric materials, with either carbohydrates or functional groups such as alkynes or alkenes. LÄS MER

  3. 2. Carbohydrate-Functionalized Nanomaterials : Synthesis, Characterization and Biorecognition Studies

    Författare :Na Kong; Mingdi Yan; Joseph J. Barchi Jr; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbohydrate; glyconanomaterials; perfluorophenyl azide PFPA ; CuAAC; AAAC; coupling chemistry; 19 F q NMR; lectin; carbon nanomaterials; microwave irradiation; Kemi; Chemistry; Bioteknologi; Biotechnology;

    Sammanfattning : This thesis focuses on the development of carbohydrate coupling chemistry on nanomaterials and their biological activity studies. It is divided into two parts:In part one, two carbohydrate immobilization approaches, based on perfluorophenyl azide (PFPA)-functionalized silica nanoparticles (SNPs), are presented, where the binding affinity of the glyconanoparticles was evaluated through carbohydrate-lectin interaction. LÄS MER

  4. 3. Novel Porous Films from Functional and Biocompatible Linear-Dendritic Hybrids

    Författare :Marie V. Walter; Michael Malkoch; Steve P. Rannard; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; poly ethylene glycol ; poly caprolactone ; linear-dendritic hybrid; click chemistry; CuAAC; thiol-ene chemistry; amphiphilic polymer; honeycomb film; isoporous film; thiol; dendrimer;

    Sammanfattning : In the last decades, the fabrication of ordered nano- and microporous structures has attracted increasing interest due to their specific properties and multiple possible applications in electronics, as templates or in the biological field. The development of such materials has been favored by the introduction of the simple breath-figure templating method in the 1990’s. LÄS MER

  5. 4. Synthesis of Nitrogen Heterocycles via 1,3-Dipolar Cycloadditions - Method Development and Applications

    Författare :Johan Johansson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2D NOESY; alkyne; 3-dipolar cycloaddition; azomethine ylide; 1; CNTs; azide; sequential one-pot; SEM EDS; microwave heating; RuAAC; CuAAC;

    Sammanfattning : Because of the diverse properties displayed by nitrogen heterocycles, they are one of the most commonly used structural elements in drug discovery. Due to this variation in properties, however, the chemistry and synthetic pathway to each heterocycle is unique. LÄS MER

  7. 5. Functional Dendritic Materials using Click Chemistry : Synthesis, Characterizations and Applications

    Författare :Per Antoni; Anders Hult; Michael Malkoch; Stefan Hecht; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dendrimer; Dendron; Dendritic; Hyperbranched; Click; Chemistry; CuAAc; One-Pot; Multi-functional; Simultaneous; Honeycomb; Isoporous; MALDI; NMR; GPC; TGA; DSC; Polymer chemistry; Polymerkemi;

    Sammanfattning : Förfrågan efter nya och mer avancerade applikationer är en pågående process vilket leder till en konstant utveckling av nya material. För att förstå relationen mellan en applikations egenskaper och dess sammansättning krävs full förståelse och kontroll över materialets uppbyggnad. LÄS MER