Sökning: "autoregulation"

Visar resultat 26 - 30 av 30 avhandlingar innehållade ordet autoregulation.

  1. 26. Tryptophan photoproducts : regulation of CYP1A1 transcription and modulation of cell growth

    Författare :Yu-Dan Wei; Dieter Schrenk; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; toxikologisk genetik; Genetic Toxicology;

    Sammanfattning : The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the regulation of many drug-metabolizing enzymes. The regulation of cytochrome P4501A1 (CYP1A1) has been most intensively studied. LÄS MER

  2. 27. Gluco- and mineralocorticoid receptor regulation of regional brain neurotrophism

    Författare :Anita Christiane Hansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurotrophins; BDNF; NT-3; bFGF; FGF receptor; immediate early genes; c-fos; antisense oligodeoxynucleotides; adrenalectomy; stress; glucocorticoids; mineralocorticoids; glucocorticoid receptor; mineralocorticoid; receptor in situ hybridization.;

    Sammanfattning : Gluco- and mineralocorticoid hormones exert powerful actions on brain function and are important in the mediation of the stress response and the survival of hippocampal neurons. The aim of this thesis was to study the influence of glucocorticoid (GR)/mineralocorticoid receptor (MR) actions on brain neurotrophism including analyses of immediate early genes (IEGs) and of feedback responses on GR and/or MR. LÄS MER

  3. 28. Intrinsic and extrinsic protection of the brain

    Författare :Peter Kimme; Olof Grände; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The brain is a complex organ and critically dependent on its oxygen metabolism and blood supply. The purpose of the present study was twofold: firstly to design, evaluate, and adopt a physiologically stable experimental model for repeated measurements of cerebral cortical microvascular perfusion by a new laser Doppler technique (experimental part (I) - intrinsic model). LÄS MER

  4. 29. Regulation of the Epstein-Barr Virus Latent Membrane Protein 1 Expression

    Författare :Pegah Johansson; Göteborgs universitet; []
    Nyckelord :Gene regulation; LMP1; Epstein-Barr virus; Herpesvirus;

    Sammanfattning : Epstein-Barr virus (EBV) is a probably the most effective and successful human virus, infecting more than 90% of the world?s adult population. As with the other members of the herpesvirus family, EBV establishes latent infection in its host and persists life-long. LÄS MER

  5. 30. Maternal renal artery Doppler velocimetry in normal and hypertensive pregnancies

    Författare :Marius Kublickas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atrial natriuretic factor Cyclicguanosine monophosphate Doppler ultrasoundKidney Modeling Preeclampsia Pregnancy Preg-nancy induced hypertension Pulsatility index Re-nal artery Renal blood flow Repeatability.Stockholm 1966;

    Sammanfattning : Background: The measurement of effective renal plasma flow (ERPF) by calculation of p-aminohippurate (PAH) clearance is an invasive, time-consuming procedure. In nonpregnant humans, the clearance of isotopes can be used to measure renal plasma flow, but the use of these radioactive substances during pregnancy is unsuitable. LÄS MER