Sökning: "arenas"

Visar resultat 1 - 5 av 286 avhandlingar innehållade ordet arenas.

1. 1. Sensitivity, Noise and Detection of Enzyme Inhibition in Progress Curves

   Författare :Omar Gutierrez Arenas; Helena Danielson; Athel Cornish-Bowden; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Progress curves; limit of detection; Z -factor; primary screening; enzyme inhibition; error structure; sensitivity analysis; High-throughput screning; Biokemi;

   Sammanfattning : Starting with the development of an enzymatic assay, where an enzyme in solution hydrolysed a solid-phase bound peptide, a model for the kinetics of enzyme action was introduced. This model allowed the estimation of kinetic parameters and enzyme activity for a system that has the peculiarity of not being saturable with the substrate, but with the enzyme. LÄS MER

3. 2. Modeling Biochemical Network Involved in Striatal Dopamine Signaling

   Författare :Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez Arenas; Upinder Singh Bhalla; Jakob Kisbye Dreyer; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine signaling; Striatum; Reward learning; Acetylcholine; Mass-action modeling; FRET biosensor; Adenosine; Eligibility trace; Computer Science; Datalogi;

   Sammanfattning : In this thesis, I studied the molecular integration of reward-learning related neuromodulatory inputs by striatal medium-sized projection neurons (MSNs) using mass-action kinetic modeling.It is known that, in reward learning, an unexpected reward results in transient elevation in dopamine (peak) whereas omission of an expected reward leads to transient dopamine decrease (dip). LÄS MER

4. 3. Modeling receptor induced signaling in MSNs : Interaction between molecules involved in striatal synaptic plasticity

   Författare :Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez-Arenas; Upinder S. Bhalla; Pierre Vincent; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatal synaptic plasticity; LTP; Dopamine; Acetylcholine; Synergy; Medium spiny neurons; MSNs;

   Sammanfattning : Basal Ganglia are evolutionarily conserved brain nuclei involved in several physiologically important animal behaviors like motor control and reward learning. Striatum, which is the input nuclei of basal ganglia, integrates inputs from several neurons, like cortical and thalamic glutamatergic input and local GABAergic inputs. LÄS MER

5. 4. La subjetividad Oculta : La representación del amor en obras de sor Francisca Josefa de Castillo y Soledad Acosta de Samper

   Författare :María Eugenia Osorio Soto; Eva Löfquist; Ángeles Encinar; Flor María Rodríguez Arenas; Stockholms universitet; []
   Nyckelord :Confessional discourse; Eros; Agape; interior experience; experience of boundaries; emergence and circulation of discourse; poetics of social texts; sociotexto; romantic subjectivity; illness as a metaphor; ostracism; internalization of the masculine point of view;

   Sammanfattning : The aim of this thesis is to study the romantic discourse present in two literary genres, two authors and two time periods: the works of the Mystic Francisca Josefa de Castillo, Su Vida and Afectos Spirituales, both written during the colonial period, and the romantic novel, Dolores. Cuadros en la vida de una mujer (1867) by Soledad Acosta de Samper. LÄS MER

7. 5. Marine seaweed invasions : Impacts and biotic resistance in native ecosystems

   Författare :Josefin Sagerman; Sofia Wikström; Fransisco Arenas; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant invasion; exotic species; generalist herbivores; plant-herbivore interactions; enemy-release hypothesis; ecosystem function; marin ekotoxikologi; Marine Ecotoxicology;

   Sammanfattning : Marine seaweeds constitute one of the most productive plant systems known on Earth and a rich fauna including juvenile fish and crustaceans is dependent on the habitats they form. Human influence on marine costal ecosystems has resulted in large scale changes to the abundance and distribution of species, where species introductions constitute an obvious part. LÄS MER