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Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Surgery for rectal cancer : the impact of perioperative factors

    Författare :Daniel Kverneng Hultberg; Martin Rutegård; Jörgen Rutegård; Peter Matthiessen; Markku Haapamäki; Lydrup Marie-Louise; Tom Öresland; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; abdominal surgery; anastomotic leakage; anastomotic dehiscence; postoperative complications; vascular tie; ligation level; oncologic outcome; surgical oncology; survival; recurrence; functional outcome; urogenital; anorectal; incontinence; NSAID; COX; Surgery; kirurgi;

    Sammanfattning : Rectal cancer is one of the most common and deadly cancer forms worldwide. A large proportion of rectal cancer patients are surgically treated with curative intention, with anterior resection being the most frequently used method today. LÄS MER

  2. 2. Experimental Colonic Obstruction and Anastomotic Healing

    Författare :Martin Rehn; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstruction; anastomosis; colon; wound healing; matrix metalloproteinases; collagen; MMP inhibition;

    Sammanfattning : Colorectal cancer is one of the most common malignant diseases world-wide. Most patients can be diagnosed, staged and treated by surgery in an elective setting. However, about one fifth of the patients will have an emergency presentation and in most cases due to malignant obstruction of the left colon. LÄS MER

  3. 3. Permanent stoma after anterior resection for rectal cancer : prevalence and mechanisms

    Författare :Klas Holmgren; Martin Rutegård; Jörgen Rutegård; Markku M. Haapamäki; Peter Matthiessen; Malin Sund; Per J. Nilsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rectal cancer; anterior resection; permanent stoma; defunctioning stoma; mesorectal excision; biomarkers; Surgery; kirurgi;

    Sammanfattning : While sphincter-saving surgery constitutes standard treatment for rectal cancer, anterior resection still harbours a significant risk of a permanent stoma in the long run. Although anastomotic leakage plays a major role in this surgical dilemma, the exact mechanisms are not known, while surveys indicate a stoma-free outcome is essential for a majority of patients. LÄS MER

  4. 4. Aspects on diverticular disease

    Författare :Fredrik Hjern; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Diverticular disease; diverticulitis; risk factors; antibiotics; CT colonography; colonoscopy; genital fistula; medical and surgical treatment;

    Sammanfattning : Objective: The aims of this thesis were to evaluate the influence of ethnicity and other sociodemographic factors on the rate of diverticular disease (DD) (Paper I), to compare findings specific for DD and acceptance of CT Colonography (CTC) and conventional Colonoscopy (CC) in patients examined after diverticulitis (AD) (Paper II), to evaluate the value of antibiotics in conservative treatment of patients with mild AD (Paper III) and to study patients with diverticular fistulas to the female genital tract (Paper IV). Methods: In paper I, Swedish national registers with information about health and socio-demographic indicators were used to study ethnicity and other socio-demographic factors and the risk of hospital admission due to DD in a national cohort (4. LÄS MER