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Visar resultat 6 - 10 av 20 avhandlingar som matchar ovanstående sökkriterier.
6. GABA-steroid effects in healthy subjects and women with polycystic ovary syndrome
Sammanfattning : Background: The progesterone metabolite allopregnanolone is involved in several clinical conditions in women, e.g. premenstrual dysphoric disorder. It is a very potent GABA-steroid with GABA-A receptor effects similar to other GABA-agonists, e. LÄS MER
7. Progesterone metabolites : learning, tolerance, antagonism & metabolism
Sammanfattning : Progesterone metabolites as allopregnanolone, isoallopregnanolone and tetrahydrodeoxy-corticosterone (THDOC) are increased in the luteal phase of the menstrual cycle, throughout pregnancy and during stress. Allopregnanolone and THDOC are neurosteroids with 3α-hydroxy, 5α-configurations and positive modulating effect on the GABAA receptor. LÄS MER
8. Neuroactive steroids and rat CNS
Sammanfattning : Several studies suggest profound effects on mood and cognition by neuroactive steroids. Estrogen alone or in combination with antidepressant drugs affecting the serotonin system has been used to treat mood disorders. On the other hand, progesterone is related to negative effects on mood and memory. LÄS MER
9. Premenstrual dysphoric disorder in relation to neuroactive steroids and alcohol
Sammanfattning : Introduction: Premenstrual Dysphoric Disorder (PMDD) is a condition that affects about 2-6% of women of reproductive age. The relation to ovarian steroids is apparent as symptoms are absent during anovulatory cycles. LÄS MER
10. Physiological Stress Reactivity in Late Pregnancy
Sammanfattning : During pregnancy, the basal activity is increased in both of our major stress response systems: the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis. At the same time, the reactivity towards stressors is reduced. These alterations sustain maternal and fetal homeostasis, and are involved in the regulation of gestational length. LÄS MER