Sökning: "acute toxicity"

Visar resultat 16 - 20 av 85 avhandlingar innehållade orden acute toxicity.

  1. 16. Neurotoxic Effects of Dichlorophenyl Methylsulphones Related to Olfactory Mucosal Lesions

    Författare :Carina Carlsson; Ingvar Brandt; Hans Tjälve; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; olfcatory toxicity; olfactory bulb; aryl methylsulphone; neurotoxicity; QSAR; Biologi; Biology; Biologi; Ecotoxicology; Ekotoxikologi;

    Sammanfattning : This thesis deals with the highly potent olfactory mucosa toxicant 2,6-dichlorophenyl methylsulphone (2,6-diClPh-MeSO2) and its non-toxic 2,5-chlorinated isomer (2,5-diClPh-MeSO2). In mice, both substances bind firmly in the olfactory mucosa and the olfactory bulb, which are important components of the sensory system. LÄS MER

  3. 17. Methodology for evaluation of hazards from solid waste and landfill-generated leachate

    Författare :Britt-Marie Svensson; Lennart Mathiasson; Lennart Mårtensson; Ann-Sofi Rehnstam-Holm; Kenneth M. Persson; Högskolan Kristianstad; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Analytical protocol; organic pollutants; toxicity test; landfill leachate; leachate treatment; leaching test; waste acceptance criteria; Chemistry; Kemi; NATURAL SCIENCES; NATURVETENSKAP; leaching test; waste acceptance criteria.;

    Sammanfattning : A methodology based on an analytical protocol for evaluation of hazards from landfill leachate and solid waste is described. A dynamic analytical protocol, the LAQUA protocol, including measurements of inorganic and water-quality parameters, polar and non-polar organic marker compounds, and toxicity, was constructed. LÄS MER

  4. 18. Methodology for evaluation of hazards from solid waste and landfill generated leachate

    Författare :Britt-Marie Svensson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; leaching test; waste acceptance criteria.; leachate treatment; landfill leachate; toxicity test; Analytical protocol; organic pollutants;

    Sammanfattning : A methodology based on an analytical protocol for evaluation of hazards from landfill leachate and solid waste is described. A dynamic analytical protocol, the LAQUA protocol, including measurements of inorganic and water-quality parameters, polar and non-polar organic marker compounds, and toxicity, was constructed. LÄS MER

  5. 19. Acute lung failure induced by tricyclic antidepressants : an experimental evaluation

    Författare :Karin Svens; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ARDS; tricyclic antidepressants; isolated lungs; rat; endothelin; endothelial cells; tight junctions;

    Sammanfattning : The tricyclic antidepressant drugs (TCA) have, over the years, been reported to be able to cause adult respiratory distress syndrome (ARDS)/acute lung injury in connection with overdose, and are currently among the most common cause of self-poisoning. Approximately 10% of all TCA overdose patients develop ARDS, and the treatment of these patients, irrespective of the event causing ARDS, is mainly supportive. LÄS MER

  7. 20. Metal homeostasis as critical determinant for cellular fitness

    Författare :Jutta Diessl; Sabrina Büttner; Rajini Rao; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metal homeostasis; manganese toxicity; coenzyme Q synthesis; mitochondrial respiration; calcineurin signaling; Pmr1; SPCA1; calcium; survival; caloric restriction; Parkinson’s disease models; proteotoxicity; Pep4; cathepsin D; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Metals play a crucial role in cellular biology. Bulk and trace metals such as calcium and manganese regulate a plethora of cellular processes ranging from signaling and oxidative stress to proteostasis and energy metabolism. LÄS MER