Sökning: "Zinc finger"

Visar resultat 6 - 10 av 50 avhandlingar innehållade orden Zinc finger.

  1. 6. Human adenovirus – host cell interplay : The role of the cellular zinc finger proteins and mitochondrial DNA

    Författare :Kwangchol Mun; Tanel Punga; Stefan Schwartz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Adenovirus; Protein VII; Ubiquitination; Chromatin remodeling; Mitochondria;

    Sammanfattning : Human adenovirus (HAdV) is an abundant DNA virus with significant clinical relevance since it cauces a variety of respiratory, ocular, and gastrointestinal diseases. It is also intensively used as a therapeutic tool to treat cancers and to boost immune responses. LÄS MER

  3. 7. Molecular studies of Wig-1, a p53-induced zinc finger protein

    Författare :Cristina Méndez Vidal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The fact that p53 is one of the most commonly mutated gene in human tumors indicates that it has a key role in tumor suppression. p53 accumulates after DNA-damage and other types of cellular stress, leading to the initiation of a p53-dependent biological response, including cell cycle arrest and apoptosis. LÄS MER

  4. 8. Development of improved nuclear magnetic resonance techniques and structure determination of a zinc finger peptide

    Författare :Anna Hammarström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Since the functions of biological molecules are closely related to their structures, obtaining the three-dimensional structures is of great importance to the understanding of biology. Currently, the only two methods that can be used for protein structure determination at atomic resolution are X-ray crystallography and NMR spectroscopy. LÄS MER

  5. 9. Probabilistic Modelling of Domain and Gene Evolution

    Författare :Sayyed Auwn Muhammad; Jens Lagergren; Bastien Boussau; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phylogenetics; Phylogenomics; Evolution; Domain Evolution; Gene tree; Domain tree; Bayesian Inference; Markov Chain Monte Carlo; Homology Inference; Gene families; C2H2 Zinc-Finger; Reelin Protein; Computer Science; Datalogi;

    Sammanfattning : Phylogenetic inference relies heavily on statistical models that have been extended and refined over the past years into complex hierarchical models to capture the intricacies of evolutionary processes. The wealth of information in the form of fully sequenced genomes has led to the development of methods that are used to reconstruct the gene and species evolutionary histories in greater and more accurate detail. LÄS MER

  7. 10. Function and regulation of the Yeast Mig1 repressor

    Författare :Jonas Östling; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; glucose repression; Mig1; zinc finger protein; Saccharomyces cerevisiae; Kluyveromyces marxianus; Snf1; Biokemi; Biochemistry; Biokemi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Glucose repression is a global regulatory response in the yeast Saccharomyces cerevisiae. Thus, in the presence of glucose, the preferred carbon source, expression of many genes encoding proteins required for metabolism of other carbon sources are turned off.An important mediator of glucose repression is the Mig1 repressor. LÄS MER